Age-specific and sexual variability of morphological and biomechanical parameters of anterior cerebral artery of adults

In the experiment on monoaxonic longitudinal distension by tensile-testing machine Tira Test 28005 (Germany) with loading unit - 100 N the general rigidity, breaking point and relative lengthening of anterior cerebral artery (ACA ) of adult people have been under study. Under the microscope on transverse sections the external diameter of the artery, its wall thickness have been measured and diameter of lumen have been calculated. In total 228 ACA (132 - from corpses of men, 92 - from corpses of women) have been investigated. They have been received in 16 hours after autopsy of adult people whose cause of death has not been connected with vascular cerebral pathology. It has been revealed that right ACA is longer and narrower than left one. ACA s wall length and thickness predominate in men in comparison with women in average of 5,4 - 13,0%. With years ACA lengthens, its external diameter increases. Biomechanical parameters of ACA s wall do not have any authentic sexual differences, they dont depend on the side of the arterial ring. With years the rigidity of ACA decreases, especially in middle age. In old age its general rigidity increases. It is connected with the increase of ACA s wall thickness. The ability of ACA to lengthening doesnt depend upon age. Experimental findings may be used as criteria of age standard of morphological and biomechanical parameters of ACA.