Age-related changes of the profile field of neurons of the area 7 of the brain of men and women in the process of the aging

The aim of the work is to study changes in the profile field of pyramidal neurons in the cortex of field 7 of the brain of men and women in the aging process. A cytoarchitectonic study of the cortex of field 7 of the upper parietal region of the brain of men and women was carried out on a series of frontal paraffin sections stained by the Nissl method. The brain preparations of men and women of three age groups were studied: the groups of mature age (from 20 to 60 years), the elderly group (from 60 to 75 years) and the group of senile age (from 75 years and older). In each age group, 5 preparations of the male brain and 5 preparations of the female brain were studied. Age-related changes in the cytoarchitectonics of the profile field of pyramidal neurons in the cytoarchitectonic layers of the third and fifth cortex fields 7 of the brain of men and women were studied. As a result of the study, it was revealed that in the process of aging of the brain of men and women, changes in similar morphometric indicators of field 7 cortex occur at different age periods, the dynamics of age-related changes in functionally different cytoarchitectonic layers III and V of the cerebral cortex of men and women are also different.