Age-related changes of vitamins A and E content in rats’ organs under modified light condition and exogenic melatonin

The influence of melatonin on vitamins A and E content in organs (liver, kidney, heart) of 6, 12, and 18-months old rats under different light conditions was studied. The present research has demonstrated that vitamins’ level in rats’ tissues depends on light conditions. As a result, the most significant changes in the antioxidant system were revealed under constant and natural light exposure. The level of vitamin E in the liver of the 6-months old rats was significantly higher than in the other groups due to constant light condition. Addition of melatonin and constant light condition had no influence on vitamin E concentration in the heart of the rats. The exception took place in natural light condition under which introduction of melatonin increased vitamin E content. Melatonin supplementation had a positive influence on vitamins A and E level in rats’ tissues, decreased changes in the antioxidant system, and reduced antioxidant deficit in the organisms.