Аutologous transplantation in patients with lymphoproliferative diseases: does everyone manage to get a sufficient number of peripheral hematopoietic stem cells?
Автор: Fedyk O.V., Sarzhevsky V.A., Melnichenko V.Yu., Dubinina U.N., Mochkin N.E., Smirnova E.G., Kolesnikova D.S., Bannikova A.E.
Журнал: Вестник Национального медико-хирургического центра им. Н.И. Пирогова @vestnik-pirogov-center
Рубрика: Оригинальные статьи
Статья в выпуске: 3 т.13, 2018 года.
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103 patients with LD were included in this study. The mobilization of PBSC with only colony-stimulating factors (CSF) was carried out for 91 patients, chemotherapy in combination with CSF - for 12 patients. The concentration of CD34+ in peripheral blood (PB) was studied on the day of the intended cytapheresis. Cytapheresis was commenced when CD34 + concentration had been greater than 0.01 x 106 cells/ml. 22% of lymphoma patients with indications for high-dose chemotherapy and autoHSCT are "poor mobilizers”. A possible contributing factor to poor mobilization is sex of patients.
Mobilization of peripheral stem cells, lymphoproliferative diseases, autologous transplantation
Короткий адрес: https://sciup.org/140237234
IDR: 140237234 | DOI: 10.25881/BPNMSC.2018.23.56.014
