Correlation of monoamine oxidase B activity and number of astrocytes in the developing human brain

Dynamics of monoamine oxidase B activity and the number of astrocytes in fetuses of the second half of gestation as well as during the early periods of postnatal ontogenesis (n=153) occurring in the various compartments of the human brain have been studied. Simultaneous increase of the studied indices was noted. The most pronounced dynamics was revealed in the hypothalamus mamillary bodies, where age-specific dynamics of enzyme activity directly correlated with the increase of the number of astrocytes. Age-related increase in the activity of bridge structures, medulla and cerebellum not correlate with the number of astrocytes in the brain compartments. This pattern is qualitatively consistent with the dynamics of the number of glial cells and the activity of MAOB people mature, middle and old age.