The Significance of Spontaneous Immunoglobulin-Synthesizing Activity of b-Lymphocytes in Urogenital Reactive Arthritis, Depending on the Course of the Disease

This work considers the significance of spontaneous immunoglobulin-synthesizing activity of B-lymphocytes (SIAL) in various clinical variants of urogenital reactive arthritis (UReA). It was found that an increased level of SIAL was found in patients with autoimmune diseases (AS, RA and SLE) from 72.2% to 88.8%, in 57.9% of patients with UReA, only 10% of healthy individuals, and only 27.3% of patients with osteoarthritis. It was shown that UReA with a high degree of activity and a chronic course of the disease, the values of SIAL were higher than with minimal and moderate degrees of activity and acute and prolonged courses of the disease.