Adrenergic and serotoninergic activity of a new antimigraine compound
Автор: Morkovina Ya. V., Semenova Yu. V., Salikhov D.A., Maltsev D.V., Yakovlev D.S.
Журнал: Волгоградский научно-медицинский журнал @bulletin-volgmed
Рубрика: Фармакология токсикология
Статья в выпуске: 1 (53), 2017 года.
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We studied adrenergic and serotoninergic properties of the 9-diethylaminoethyl-2-(4-iriethoxyphenyl)iiTiidazo[1,2-a]benzimidazole molecule. The compound has been shown to exhibit potent serotonin-blocking activity in the isolated rat uterus and in the 5-HTP-hyperkinesis test. In vitro and in vivo studies have shown that the compound has weak adreno-blocking activity.
5-нт2a-рецепторы, serotonin, 5-ht2a-receptors, а-adrenoreceptors, 5-htp-induced hyperkinesis, reserpine-induced hypothermia, isolated organs
Короткий адрес: https://sciup.org/142149208
IDR: 142149208
