Errors in automated triage of preventive chest scans: main causes and potential reduction strategies

Introduction. The high prevalence of chest X-ray and fluorographic examinations creates significant workload for the radiology department. One promising solution for optimizing the preventive radiography and fluorography pipelines is employing artificial intelligence (AI) technologies. This approach demonstrates effectiveness in triaging studies based on binary assessment (“normal”/”abnormal”). Evaluation of this method identified shortcomings in the form of false-negative results requiring further study and improvement. Aim: To evaluate potential methods for reducing false-negative results in automated triage of preventive chest radiographic examinations using AI-powered software. Material and Methods. In a retrospective diagnostic study conducted from May 1, 2025, to June 30, 2025, we analyzed 411 cases of false-negative results identified during evaluation of automated triage powered by three different AI models. The study utilized data from preventive chest radiographic examinations performed in outpatient setting and mass screening examinations of the adult population in Moscow. Images were re-analyzed by two expert radiologists (> 10 years of experience) considering the available clinical information and patient history data. Analytical and descriptive statistical methods were used. Results. The majority (n = 266) of false-negative results were associated with missed infiltrative changes and pulmonary foci. The remaining clinically significant discrepancies were observed in 24 cases. Analysis of archival data and patient histories identified additional information that, when integrated into AI-powered services, could influence study interpretation and reduce false-negative risk. Such data were found in 68.3% of cases (n = 198) with clinically significant omissions and in 5% (n = 6) with clinically insignificant omissions. Conclusion. Reducing false-negative results requires an integrated approach: implementing duplicate AI services, improving physician referral quality, and integrating clinical data and previous patient study results into AI algorithms, necessitating development of multimodal AI software.