Antibodies and anti-antibodies specific to estradiol and progesterone and tumor proliferation in breast cancer patients
Автор: Glushkov A.N., Polenok E.G., Gordeeva L.A., Bayramov P.V., Verzhbitskaya N.E., Antonov A.V., Kolpinsky G.I., Kostyanko M.V.
Журнал: Сибирский онкологический журнал @siboncoj
Рубрика: Лабораторные и экспериментальные исследования
Статья в выпуске: 3 т.23, 2024 года.
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The study was aimed to determine the interrelations between levels of serum antibodies specific to estradiol and progesterone (IgA1-E2 and IgA1-Pg) and corresponding antiidiotypic antibodies (IgG2-E2 and IgG2-Pg) and tumor Ki67 positive cells in breast cancer patients (BCP). Material and Methods. The content of these antibodies in the blood serum of BCP (522 at the I stage and 578 at the II-IV stages) was studied using non-competitive enzyme immunoassay. Ki67 was determined using immunohistochemical method. Statistical analysis of the results was performed using the Statistica 8.0 software.
Antibodies, estradiol, progesterone, ki67, breast cancer
Короткий адрес: https://sciup.org/140305930
IDR: 140305930 | DOI: 10.21294/1814-4861-2024-23-3-73-85
