Class G antibodies specific for benzo[a]pyrene, estradiol and progesterone in women with colorectal cancer

Автор: Averyanov A.V., Antonov A.V., Zhivotovsky A.S., Kostyanko M.V., Vafin I.A., Kolpinskiy G.I.

Журнал: Сибирский онкологический журнал @siboncoj

Рубрика: Лабораторные и экспериментальные исследования

Статья в выпуске: 5 т.21, 2022 года.

Бесплатный доступ

The study was aimed to determine the level of class G antibodies specific to Bp, Es, Pg (IgG-Bp, IgG-Es, IgG-Pg) in patients with colorectal and breast cancers. Material and Methods. The content of these antibodies in the blood serum of healthy women (n=401), patients with colorectal cancer (n=219) and patients with breast cancer (n=1469) was studied using a non-competitive enzyme immunoassay. Statistical analysis of the results was performed using the Statistica 8.0 software. Results. The levels of IgG-Bp>7 and IgG-Es>6 were higher in patients with colorectal cancer than in healthy controls (66 % vs 25 %, p1, IgG-Bp/IgG-Pg>1.5, and IgG-Es/IgG-Pg>1.5 were also higher in patients with colorectal cancer than in healthy controls (74 % vs 34 %, p6 (57 % vs 33 %, p

Еще

Antibodies, benzo[a]pyrene, estradiol, progesterone, colorectal cancer, breast cancer

Короткий адрес: https://sciup.org/140296678

IDR: 140296678   |   DOI: 10.21294/1814-4861-2022-21-5-52-58

Статья научная