Assessment of platelet in case of stress-induced apnea

Автор: Mantskava M.M., Momtselidze N.G.

Журнал: Журнал стресс-физиологии и биохимии @jspb

Статья в выпуске: 3 т.10, 2014 года.

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Sleep apnea is a independent pathology and a powerful stress for the organism. Apnea is a cause of stress and strengthens the body under stress. We studied 30 men aged 34 to 57 years: 22 patients with obstructive sleep apnea and 8 patients with central sleep apnea. We explored a drop of blood in HUMACOUNT, mod. HUMACOUNT (Firm Human GmbH, Germany), bought of grant budget RF/420/7-270/12. We investigated parameters of platelet: PLT, MPV, PDWс and PCT. The analysis of the data was performed using statistical programs “Origin 4.1’’ (Microsoft. Software, Inc) and Microsoft Excel, evaluated Student and criteria Pearson. Protocol of research was adequate Helsinki Declaration. Our results in patients with obstructive apnea: PLT=109x10 9±40x10 9l; MPV =7,7±3,0fl; PCT=0,08x10 -2±0,02x10 -2%; PDWС =33,4±3,6%; in patients with central apnea - PLT=142x10 9±50x10 9l; MPV=6,4±2,0fl; PCT=0,09x10 -2±0,03x10 -2%; PDWС=32,7±3,0; in control - PLT=250x10 9±40x10 9l; MPV=11,0±4,0fl; PCT=0,25x10 -2±0,05x10 -2%; PDWС=36,2±4,0%. Interrupted we analyzed the number of platelets and platelet indices for determining homeostasis in stress disease. Stress body reduces the number of platelets. But if apnea is a disease of the fourth rank stress, platelet factors fluctuate within normal limits. Our data have practical significance for biomedicine. We propose a new marker for apnea: platelet composes.

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Central apnea, obstructive apnea, platelet, stress

Короткий адрес: https://sciup.org/14323895

IDR: 14323895

Список литературы Assessment of platelet in case of stress-induced apnea

  • Китаев-Смык Л.А. (1983) Психология стресса. М.; Наука, 365 с
  • Китаев-Смык Л.А. (2009) Психология стресса. Психологическая антропология стресса. М.; Академический Проект, 943 с
  • Davies R.J.O., Turner R., Stradling J.R. (1993) Fasting blood lipid and insulin levels in OSA patients, snorers, and matched controls. Thorax; 48, 447
  • Ehlenz K., Peter J.H., Schneider H. et al., (1990) Renin secretion is substentially influenced by obstructive sleep apnea syndrome. In: Sleep ’90. (ed) J.Horne, Bochum: Pontenagel Press: 193-195
  • He J., Kryger M.H., Zorick F.J. et al. (1988) Mortality and apnea index in obstructive sleep apnea. Experience in 385 male patients. Chest; 94, 9-14
  • Knight H., Millman R.P., Gur R.C. et al. (1987) Clinical significance of sleep apnea in the elderly. Am. Rev. Respir. Dis; 136, 845-850
  • Krieger J., Benzoni D., Sforza E., Sassard J. (1991) Urinary excretion of prostanoids during sleep in obstructive sleep apnea patients. Clin Exp. Pharmacol. Physiol; 18, 511-515
  • Nobili L, Schiavi G, Bozano E et al. (2000) Morning increase of whole blood viscosity in obstructive sleep apnea syndrome. Clin Hemorheol Microcirc; 22, 21-27
  • Palomaki H., Partinen M., Erkinjuntti T., Kaste M. (1992) Scoring, sleep apnea syndrome, and stroke. Neurology; 42, 75-81
  • Somers V.K., Mark A.L., Abboud F.M. (1988) Sympathetic activation by hypoxia and hypercapnia -implications for sleep apnea. Clin Exp Hypertens; 10, 413-422
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