Атерома дуги аорты как источник артерио-артериальной эмболии и ишемического инсульта

Автор: Рамазанов Г.Р., Трофимова А.Н., Ковалева Э.А., Шевченко Е.В.

Журнал: Вестник медицинского института "РЕАВИЗ": реабилитация, врач и здоровье @vestnik-reaviz

Статья в выпуске: 2 т.13, 2023 года.

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Введение. В настоящее время, несмотря на внедрение современных диагностических алгоритмов, у 20-40 % пациентов с ишемическим инсультом не удаётся установить его причину. Потенциальными причинами острой церебральной ишемии у пациентов с криптогенным ишемическим инсультом могут быть пароксизмальная фибрилляция предсердий, открытое овальное окно, предсердная кардиомиопатия, каротидная сеть, атерома дуги аорты, а также канцер-ассоциированная тромбофилия.Цель: систематизация данных о методах диагностики и профилактики атеромы дуги аорты.Материал и методы. Поиск литературы проводили в электронных поисковых системах Scopus, eLibrary, PubMed по ключевым словам: ишемический инсульт, криптогенный инсульт, атерома дуги аорты, патогенез ишемического инсульта.Результаты. В настоящее время, несмотря на столь детальную проработку терапевтических стратегий профилактики повторных тромботических событий у пациентов с атеромой дуги аорты, ни один из препаратов не доказал своего преимущества. Несмотря на то, что исследования NAVIGATE ESUS и RESPECT ESUS не показали превосходства пероральных антикоагулянтов над антиагрегантами в отношении предотвращения повторных ишемических инсультов у пациентов с криптогенным инсультом, было установлено, что криптогенный ишемический инсульт неоднороден, что требует дифференцированного подхода ко вторичной профилактике.Выводы. Атерома аорты может быть причиной эмболического синдрома и криптогенного инсульта. Основные методы диагностики атеромы аорты - чрезпищеводная эхокардиография и компьютерно-томографическая ангиография. Терапевтическая стратегия лечения атеромы аорты - гиполипидемическая, антитромботическая терапия в комбинации с блокаторами ренин-ангиотензин-альдостероновой системы.

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Ишемический инсульт, криптогенный инсульт, атерома дуги аорты, патогенез ишемического инсульта

Короткий адрес: https://sciup.org/143180196

IDR: 143180196 | DOI: 10.20340/vmi-rvz.2023.2.CLIN.1

Список литературы Атерома дуги аорты как источник артерио-артериальной эмболии и ишемического инсульта

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