Attractive and immunosuppressive properties of volatile secretions induced in mice separately and combine the influence of ionizing radiation and chemicals

We have studied the properties of volatile secretions induced in laboratory mice, separate or combined influence of ionizing radiation and chemical compounds (ChC), such as benzene (BZ), as well as one of the products of its metabolism - hydroquinone (GC). The reaction of preference-avoidance response in the T-maze revealed that in urine samples of mice early after exposure to ionizing radiation at doses of 2 and 4 Gy contain attractive for intact animals volatile components (VC). The introduction of BZ in a dose of 2.8 g/kg, as well as the GC in a dose of 100 mg/kg provokes the secretion of VC of aversive, repealing properties towards of intact individuals. Combined exposure to these factors leads to a reciprocal compensation of the impact of volatile secretions in the preference-avoidance response of intact mice. The examined effects depend to some extent on the dose of radiation and CC. Induced both by separate and associated exposure to radiation and CC volatile components have depressing effect of the humoral immune response, regardless of whether they are attractive or aversive properties. Induced both by separate and associated exposure to radiation and CC volatile allocation have a depressing effect of the humoral immune response, regardless of whether they are attractive or aversion properties. We are discussing the role mechanisms of chemosignaling in the development of post-radiation reactions in groups of animals.