Autosomal dominant kidney polycystosis in cats

This article considers one of the most complex nephrology cats’ diseases -autosomal dominant kidney polycystosis. Possible consequences of the development of this nephropathy in the form of chronic kidney disease are mentioned. The relationship between the development of the disease with the genetic factors is stated in the article. It is listed as the primary type of inheritance. The article presents statistical data by the incidence of nephropathy among cats of different ages. The most vulnerable breeds are mentioned: Persian, British Shorthair, exotic Shorthair, Scottish fold. The main clinical manifestations and symptoms of this pathology are: depression, vomiting, anorexia, increased thirst, changing urination frequency, increase in blood pressure, pallor of visible mucous membranes. There are presented different diagnostic methods of polycystic kidney disease. The basic laboratory tests reflecting the state of the urinary system as the disease progresses are given in the article. The special attention is paid to the explanation of the genetic basis of the method of identifying the autosomal dominant polycystic kidney disease. It focuses on the possible soft tissue damage of neighboring organs with the constant increase in the size of cysts and in the lack of well-chosen symptomatic therapy. The importance of early and timely diagnosis in order to prevent the occurrence of possible complications is described. The basic treatments depending on the stage of disease are given in the article. The conclusion about the necessity of further research on the treatment of the autosomal dominant polycystic kidney disease to stop the progression of chronic renal failure is made.