Bacteriological studies of bile and abdominal effusion in acute biliary pancreatitis

Introduction. The article presents an analysis of bacteriological studies of bile and abdominal effusion in 32 patients with acute biliary pancreatitis in the early postoperative period. Acute biliary pancreatitis accounts for up to 60 % of all cases of acute inflammation of the pancreas. Infection with destructive forms reaches 70 %, significantly increasing mortality. The current strategy of antibacterial therapy requires bacteriological confirmation of contamination.The purpose of the study. To study the risk of bacterial contamination of bile and abdominal effusion in acute biliary pancreatitis in the early postoperative period.Materials and methods. Bile and effusion samples were examined in 32 patients after laparoscopic cholecystectomy with drainage. Bacteriological studies were performed according to standard methods with an assessment of qualitative and quantitative indicators. Sampling was carried out on the first day after the operation and 3 days later.Results. The risk of bile contamination and effusion was high (43,75±8,77 % and 37,50±8,56 %, respectively). By the third day, there was a decrease in the risk of contamination to 28,13±7,95 % and 25,00±7,65 %. In patients with severe disease, a significantly high level of contamination of both media was maintained. The predominant pathogen was Escherichia coli, mainly in monoculture. The level of bacterial.Conclusion. The most common pathogen is Escherichia coli. The lowest level of antibiotic resistance was noted to fourth-generation cephalosporins, carbapenems, vancomycin.