Biochemical parameters of the intensity of systemic inflammatory response in the assessment of biocompatibility of polycaprolactone/vaterite scaffolds

In this study, we analyzed biocompatibility of polycaprolactone/vaterite scaffolds by assessing the dynamics of systemic inflammatory response. We detected an increase in the CRP level after 7 days and no changes in the level TNF-α and IL-1β after 7 and 21 days, which indicates a weak and short-term inflammatory reaction and is a pathogenetic component of matrix biocompatibility.