Biological testing of titanium-containing implants with noble metal coatings in an in vivo experiment

The aim of study is to conduct in vivo biological testing of titanium nickelide samples modified with Ag/Pt or AuAg/Pt film heterostructures in comparison with the bare carrier. Material and Methods. Titanium nickelide plates modified with film heterostructures made of noble metals and the laboratory mini-pigs used for in vivo tests were the objects of the study. To form film structures on titanium nickelide samples, the physical gas phase deposition methods: ion plasma deposition (IPD) and thermal (PVD) sputtering were used. The Ag/ Pt or AuAg/Pt heterostructures were characterized by X-ray diffraction and scanning microscopy methods.