Developmental biology of organs: organism integration and morphogenesis

Analysis of widely known publications about mechanics of being performs distinctions and common outlooks of their authors on organization of the development. This analysis allows to confirm, that hard direct connection is absent between: 1) genotype and phenotype; 2) structure and functional activity of genome and albuminous apparatus, including biosynthesis of proteins, 2а) and also between them and morphogenesis. Today available knowledges about genic organization of individuals are very limited, contradictory and not always objective. Therefore, it should be to appraise a role of gens in development of organization very carefully. I think always, that nucleinic acids are passive material of development of being, let very important, but only instrument for proteins, organizing life of this individual. Just proteins form cells, their organelles and micro-environment, intercellular contacts. It is impossible organization of tissues and organs without the latter. And for this proteins make use different substances, including nucleinic acids. I consider as important principle, that tissue integrate systems ensure formation of cells of basic types, then organism integrate system determines moulding of form, moreover changings of just organism integrate systems are fundamental driving force of morphological evolution. Results of my own investigations make it possible, that individual spatial organization is realized in process of interorganic interactions, uneven growth of organs, rats of which usually are falling in accordance with maturing of tissues. Influence of environment on development of organisms and organs (epigenetic factor) plays key role in realization of genetic information