Биология суицидальности. Близнецы и суициды

Биология суицидальности. Близнецы и суициды

Автор: Козлов В.А., Голенков А.В.

Журнал: Суицидология @suicidology

Статья в выпуске: 4 (53) т.14, 2023 года.

Бесплатный доступ

Собраны и проанализированы находящиеся в свободном доступе сведения в базе данных PubMed о суицидальном поведении близнецов. В обзоре литературы данные стратифицированы в тематические разделы о сложностях определения наследуемости при оценке суицидальности близнецов, предикторах их суицидального поведения, анализ и сопоставление реестровых исследований суицидального поведения и его ассоциациях с генетическими факторами, половой стратификации суицидального поведения, суицидальном поведении у близнецов с психическими расстройствами, результатах исследований генных ассоциаций типа случай контроль и полногеномных исследований их суицидальности. Рассмотрены генетические и эпигенетические причины дискордантности монозиготных близнецов. Сформированный к настоящему времени пул исследований позволяет сделать вывод, что суицидальное поведение у близнецов наследуемо и рано проявляет себя комплексом вербальных поведенческих предикторов. Базовой основой формирования суицидального поведения является накопление в геноме однонуклеотидных полиморфизмов, экспрессия которых ассоциирована с формированием личности и таких её черт, как повышенная агрессивность, гиперактивность, расстройство внимания. Суицидальное поведение и явные психические расстройства (биполярная депрессия, шизофрения) коморбидны, но в целом не ассоциированы.

Еще

Суицидальное поведение, психические расстройства, близнецы, монозиготы, дизиготы, наследственность, геном

Короткий адрес: https://sciup.org/140303357

IDR: 140303357   |   DOI: 10.32878/suiciderus.23-14-04(53)-3-38

Список литературы Биология суицидальности. Близнецы и суициды

  • Voracek M., Sonneck G. Surname study of suicide in Austria: differences in regional suicide rates correspond to the genetic structure of the population. Wien Klin Woch-enschr. 2007; 119 (11-12): 355-360. DOI: 10.1007/s00508-007-0787-2
  • Schulsinger F., Kety S.S., Rosenthal D., Wender P.H. A family study of suicide. In: Schou M, Stromgren E, editors. Origin, prevention and treatment of affective disorders. London: Academic Press. 1979. P. 277-287.
  • Brent D.A., Oquendo M., Birmaher B., Greenhill L., Kolko D., Stanley B., Zelazny J., Brodsky B., Bridge J., Ellis S., Salazar J.O., Mann J.J. Familial pathways to early-onset suicide attempt: risk for suicidal behavior in offspring of mood-disordered suicide attempters. Arch Gen Psychiatry. 2002; 59 (9): 801-807. DOI: 10.1001/archpsyc.59.9.801
  • Rajalin M., Hirvikoski T., Jokinen J. Family history of suicide and exposure to interpersonal violence in childhood predict suicide in male suicide attempters. J Affect Disord. 2013; 148 (1): 92-97. DOI: 10.1016/j.jad.2012.1L055
  • Brent D.A., Melhem N. Familial transmission of suicidal behavior. Psychiatr Clin North Am. 2008; 31 (2): 157-177. DOI: 10.1016/j.psc.2008.02.001
  • Voracek M. Genetic factors in suicide: reassessment of adoption studies and individuals' beliefs about adoption study findings. PsychiatrDanub. 2007; 19 (3): 139-153.
  • Abbar M., Courtet P., Malafosse A., Castelnau D. Génétique épidémiologique et moléculaire des conduites suicidaires [Epidemiologic and molecular genetic of suicidal behavior]. Encephale. 1996; 22 Spec № 4 (1): 9-24.
  • Carlin J.B., Gurrin L.C., Sterne J.A., Morley R., Dwyer T. Regression models for twin studies: a critical review. Int J Epidemiol. 2005; 34 (5): 1089-1099. DOI: 10.1093/ije/dyi153
  • Bouchard T.J.Jr., Lykken D.T., McGue M., Segal N.L., Tellegen A. Sources of human psychological differences: the Minnesota Study of Twins Reared Apart. Science. 1990; 250 (4978): 223-228. DOI: 10.1126/science.2218526
  • Tidemalm D., Runeson B., Waern M., Frisell T., Carlstrom E., Lichtenstein P., Lângstrom N. Familial clustering of suicide risk: a total population study of 11.4 million individuals. Psychol Med. 2011; 41 (12): 2527-2434. DOI: 10.1017/S0033291711000833
  • Baldessarini R.J., Hennen J. Genetics of suicide: an overview. Harv Rev Psychiatry. 2004; 12 (1): 1-13. DOI: 10.1080/10673220490425915
  • Roy A., Rylander G., Sarchiapone M. Genetic studies of suicidal behavior. Psychiatr Clin North Am. 1997; 20 (3): 595-611. DOI: 10.1016/s0193-953x(05)70332-4
  • Roy A., Segal N.L. Suicidal behavior in twins: a replication. J Affect Disord. 2001; 66 (1): 71-74. DOI: 10.1016/s0165-0327(00)00275-5
  • Zalsman G., Frisch A., Apter A., Weizman A. Genetics of suicidal behavior: candidate association genetic approach. Isr J Psychiatry Relat Sci. 2002; 39 (4): 252-261.
  • Segal N.L. Suicidal behaviors in surviving monozygotic and dizygotic co-twins: is the nature of the co-twin's cause of death a factor? Suicide Life Threat Behav. 2009; 39 (6): 569-575. DOI: 10.1521/suli.2009.39.6.569
  • Maciejewski D.F., Creemers H.E., Lynskey M.T., Madden P.A., Heath A.C., Statham D.J., Martin N.G., Verweij K.J. Overlapping genetic and environmental influences on non-suicidal self-injury and suicidal ideation: different outcomes, same etiology? JAMA Psychiatry. 2014; 71 (6): 699-705. DOI: 10.1001/jamapsychiatry.2014.89
  • Kallmann F.J., De Porte J., De Porte E., Feingold L. Suicide in twins and only children. Am J Hum Genet. 1949; 1 (2): 113-126.
  • Carlin J.B., Gurrin L.C., Sterne J.A., Morley R., Dwyer T. Regression models for twin studies: a critical review. Int J Epidemiol. 2005; 34 (5): 1089-1099. DOI: 10.1093/ije/dyi153
  • Cardno A.G., Gottesman I.I. Twin studies of schizophrenia: from bow-and-arrow concordances to star wars Mx and functional genomics. Am J Med Genet. 2000; 97 (1): 12-17.
  • Haque F.N., Gottesman I.I., Wong A.H. Not really identical: epigenetic differences in monozygotic twins and implications for twin studies in psychiatry. Am J Med Genet C Semin Med Genet. 2009; 151 C (2): 136-141. DOI: 10.1002/ajmg.c.30206
  • Voss M., Nylen L., Floderus B., Diderichsen F., Terry P.D. Unemployment and early cause-specific mortality: a study based on the Swedish twin registry. Am J Public Health. 2004; 94 (12): 2155-2161. DOI: 10.2105/ajph.94.12.2155
  • Козлов В.А., Голенков А.В. Связь продаж алкоголя с девиантным поведением в Чувашии. Научный форум. Сибирь. 2023; 9 (2): 33-36. [Kozlov V.A., Golenkov A.V. Connection of alcohol sales with deviant behavior in Chuvashia. Scientific forum. Siberia = Nauchnyj forum. Sibir'. 2023; 9 (2): 33-36.] (In Russ)
  • Kovas Y., Galajinsky E.V., Boivin M., Harold G.T., Jones A., Lemelin J.P., Luo Y., Petrill S.A., Plomin R., Tikho-mirova T., Zhou X., Malykh S. The Russian School Twin Registry (RSTR): project PROGRESS. Twin Res Hum Genet. 2013; 16 (1): 126-133. DOI: 10.1017/thg.2012.133
  • Laing L. Black and white twins [Digital]. Mail online. 2006. https://www.dailymail.co.uk/news/article-377839/Black-white-twins.html Дата обращения: 12.11.2013
  • Moohread J. Different but the same: a story of black and white twins [Digital]. The Guardian. 2001/ https://www.theguardian. com/lifeandstyle/2011/ sep/24/twi ns-black-white Дата последнего обращения 12.11.2013
  • Shammas J. Black and white twins: Meet the sisters who "couldn't look more different if they tried" [Digital]. Mirror. 2015. Дата последнего обращения 12.11.2023
  • Li C.T., Zhao S.M., Li L. Epigenetics and its new progress in monozygotic twins. Fa Yi Xue Za Zhi. 2009; 25 (3): 212-216. Chinese.
  • Wong A.H., Gottesman I.I., Petronis A. Phenotypic differences in genetically identical organisms: the epigenetic perspective. Hum Mol Genet. 2005; 14 Spec № 1: 11-18. DOI: 10.1093/hmg/ddi116
  • Huang K. Not identical: twins studies to reveal epigenetic differences. Clin Genet. 2010; 77 (3): 228-130. DOI: 10.1111/j.1399-0004.2009.01321.x
  • Petronis A. Epigenetics and twins: three variations on the theme. Trends Genet. 2006; 22 (7): 347-350. DOI: 10.1016/j.tig.2006.04.010
  • Dixon-Salazar T., Silhavy J.L., Marsh S.E., Louie C.M., Scott L.C., Gururaj A., Al-Gazali L., Al-Tawari A.A., Kayserili H., Sztriha L., Gleeson J.G. Mutations in the AHI1 gene, encoding jouberin, cause Joubert syndrome with cortical polymicrogyria. Am J Hum Genet. 2004; 75 (6): 979-987. DOI: 10.1086/425985
  • Fisher H.L., Murphy T.M., Arseneault L., Caspi A., Mof-fitt T.E., Viana J., Hannon E., Pidsley R., Burrage J., Dempster E.L., Wong C.C., Pariante C.M., Mill J. Methylomic analysis of monozygotic twins discordant for childhood psychotic symptoms. Epigenetics. 2015; 10 (11): 1014-1023. DOI: 10.1080/15592294.2015.1099797
  • Csankovszki G., Nagy A., Jaenisch R. Synergism of Xist RNA, DNA methylation, and histone hypoacetylation in maintaining X chromosome inactivation. J Cell Biol. 2001; 153 (4): 773-784. DOI: 10.1083/jcb.153.4.773
  • Heisler L.E., Torti D., Boutros P.C., Watson J., Chan C., Winegarden N., Takahashi M., Yau P., Huang T.H., Farn-ham P.J., Jurisica I., Woodgett J.R., Bremner R., Penn L.Z., Der S.D. CpG Island microarray probe sequences derived from a physical library are representative of CpG Islands annotated on the human genome. Nucleic Acids Res. 2005; 33 (9): 2952-2961. DOI: 10.1093/nar/gki582
  • Kaminsky Z.A., Tang T., Wang S.C., Ptak C., Oh G.H., Wong A.H., Feldcamp L.A., Virtanen C., Halfvarson J., Tysk C., McRae A.F., Visscher P.M., Montgomery G.W., Gottesman I.I., Martin N.G., Petronis A. DNA methylation profiles in monozygotic and dizygotic twins. Nat Genet. 2009; 41 (2): 240-245. DOI: 10.1038/ng.286
  • Ollikainen M., Smith K.R., Joo E.J., Ng H.K., Andronikos R., Novakovic B., Abdul Aziz N.K., Carlin J.B., Morley R., Saffery R., Craig J.M. DNA methylation analysis of multiple tissues from newborn twins reveals both genetic and intrauterine components to variation in the human neonatal epigenome. Hum Mol Genet. 2010; 19 (21): 41764188. DOI: 10.1093/hmg/ddq336
  • Rolf B., Krawczak M. The germlines of male monozygotic (MZ) twins: Very similar, but not identical. Forensic Sci Int Genet. 2021; 50: 102408. DOI: 10.1016/j.fsigen.2020.102408
  • O'Reilly L.M., Pettersson E., Quinn P.D., Klonsky E.D., Lundström S., Larsson H., Lichtenstein P., D'Onofrio B.M. The association between general childhood psycho-pathology and adolescent suicide attempt and self-harm: A prospective, population-based twin study. J Abnorm Psychol. 2020; 129 (4): 364-375. DOI: 10.1037/abn0000512
  • O'Hare K.J.M., Korhonen T., Latvala A., Kaprio J., Lin-scott R.J. Association of subclinical psychosis with suicidal ideation: A twin study. Schizophr Res. 2020; 223: 173178. DOI: 10.1016/j.schres.2020.07.010
  • Sarkisian K., Van Hulle C., Goldsmith H.H. Persistence during childhood problem-solving as a predictor of active suicidal ideation during adolescence. Res Child Adolesc Psychopathol. 2021; 49 (4): 533-543. DOI: 10.1007/s10802-020-00726-4
  • Wade T.D., Fairweather-Schmidt A.K., Zhu G., Martin N.G. Does shared genetic risk contribute to the cooccurrence of eating disorders and suicidality? Int J Eat Disord. 2015; 48 (6): 684-691. DOI: 10.1002/eat.22421
  • Volk H.E., Todd R.D. Does the Child Behavior Checklist juvenile bipolar disorder phenotype identify bipolar disorder? Biol Psychiatry. 2007; 62 (2): 115-120. DOI: 10.1016/j.biopsych.2006.05.036
  • Evins A.E., Korhonen T., Kinnunen T.H., Kaprio J. Prospective association between tobacco smoking and death by suicide: a competing risks hazard analysis in a large twin cohort with 35-year follow-up. Psychol Med. 2017; 47 (12): 2143-2154. DOI: 10.1017/S0033291717000587
  • Scherrer J.F., Grant J.D., Agrawal A., et al. Suicidal behavior, smoking, and familial vulnerability. Nicotine Tob Res. 2012; 14 (4): 415-424. DOI: 10.1093/ntr/ntr230
  • Few L.R., Werner K.B., Sartor C.E., et al. Early onset alcohol use and self-harm: a discordant twin analysis. Alcohol Clin Exp Res. 2015; 39 (11): 2134-2142. DOI: 10.1111/acer.12889
  • Whitfield J.B., Pang D., Bucholz K.K., Madden P.A., Heath A.C., Statham D.J., Martin N.G. Monoamine oxidase: associations with alcohol dependence, smoking and other measures of psychopathology. Psychol Med. 2000; 30 (2): 443-454. DOI: 10.1017/s0033291799001798
  • Sarkisian K.L., Van Hulle C.A., Hill Goldsmith H. Brooding, inattention, and impulsivity as predictors of adolescent suicidal ideation. J Abnorm Child Psychol. 2019; 47 (2): 333-344. DOI: 10.1007/s10802-018-0435-5
  • Statham D.J., Heath A.C., Madden P.A., Bucholz K.K., Bierut L., Dinwiddie S.H., Slutske W.S., Dunne M.P., Martin N.G. Suicidal behaviour: an epidemiological and genetic study. Psychol Med. 1998; 28 (4): 839-855. DOI: 10.1017/s0033291798006916
  • Tomassini C., Juel K., Holm N.V., Skytthe A., Christensen K. Risk of suicide in twins: 51 year follow up study. BMJ. 2003; 327 (7411): 373-374. DOI: 10.1136/bmj.327.7411.373
  • Buttenschen H.N., Flint T.J., Foldager L., Qin P., Christoffersen S., Hansen N.F., Kristensen I.B., Mortensen P.B., Berglum A.D., Mors O. An association study of suicide and candidate genes in the serotonergic system. J Affect Disord. 2013; 148 (2-3): 291-298. DOI: 10.1016/j.jad.2012.12.011
  • Sack G.D. Risk of suicide in twins: suicide has social side. BMJ. 2003; 327 (7424): 1168-11689; author reply 1169. DOI: 10.1136/bmj.327.7424.1168-c
  • Edwards A.C., Ohlsson H., Moscicki E., Crump C., Sundquist J., Lichtenstein P., Kendler K.S., Sundquist K. On the genetic and environmental relationship between suicide attempt and death by suicide. Am J Psychiatry. 2021; 178 (11): 1060-1069. DOI: 10.1176/appi.ajp.2020.20121705
  • Voracek M., Loibl L.M. Genetics of suicide: a systematic review of twin studies. Wien Klin Wochenschr. 2007; 119 (15-16): 463-475. DOI: 10.1007/s00508-007-0823-2
  • Lynskey M.T., Glowinski A.L., Todorov A.A., Bucholz K.K., Madden P.A., Nelson E.C., Statham D.J., Martin N.G., Heath A.C. Major depressive disorder, suicidal ideation, and suicide attempt in twins discordant for cannabis dependence and early-onset cannabis use. Arch Gen Psychiatry. 2004; 61 (10): 1026-1032. DOI: 10.1001/archpsyc.61.10.1026
  • Linker J., Gillespie N.A., Maes H., Eaves L., Silberg J.L. Suicidal ideation, depression, and conduct disorder in a sample of adolescent and young adult twins. Suicide Life Threat Behav. 2012; 42 (4): 426-436. DOI: 10.1111/j.1943-278X.2012.00101.x
  • Forsberg C.W., Estrada S.A., Baraff A., et al. Risk factors for suicide in the Vietnam - era twin registry. Suicide Life Threat Behav. 2022; 52 (4): 631-641. DOI: 10.1111/sltb.12848
  • Fu Q., Heath A.C., Bucholz K.K., et al. A twin study of genetic and environmental influences on suicidality in men. Psychol Med. 2002; 32 (1): 11-24. DOI: 10.1017/s0033291701004846
  • Lobo I. Multifactorial inheritance and genetic disease. Nature Education. 2008; 1 (1): 5.
  • Tidemalm D., Runeson B., Waern M., et al. Familial clustering of suicide risk: a total population study of 11.4 million individuals. Psychol Med. 2011; 41 (12): 2527-2434. DOI: 10.1017/S0033291711000833
  • Cho H., Guo G., Iritani B.J., Hallfors D.D. Genetic contribution to suicidal behaviors and associated risk factors among adolescents in the U.S. Prev Sci. 2006; 7 (3): 303311. DOI: 10.1007/s11121-006-0042-5
  • DiBlasi E., Kang J., Docherty A.R. Genetic contributions to suicidal thoughts and behaviors. Psychol Med. 2021; 51 (13): 2148-2155. DOI: 10.1017/S0033291721001720
  • Dutta R., Ball H.A., Siribaddana S.H., Sumathipala A., Samaraweera S., McGuffin P., Hotopf M. Genetic and other risk factors for suicidal ideation and the relationship with depression. Psychol Med. 2017; 47 (14): 2438-2449. DOI: 10.1017/S0033291717000940
  • Glowinski A.L., Bucholz K.K., Nelson E.C., Fu Q., Madden P.A., Reich W., Heath A.C. Suicide attempts in an adolescent female twin sample. J Am Acad Child Adolesc Psychiatry. 2001; 40 (11): 1300-1307. DOI: 10.1097/00004583-200111000-00010
  • Козлов В.А., Зотов П.Б., Голенков А.В. Суицид: генетика и патоморфоз. Монография. Тюмень: Вектор Бук, 2023. 200 с. [Kozlov V.A., Zotov P.B., Golenkov A.V. Suicide: genetics and pathomorphosis. Monography. Tyumen: Vector Book, 2023. 200 с.] (In Russ)
  • Козлов В.А., Тавинова Н.А., Голенков А.В. Склонность к отклоняющемуся поведению у студентов медицинского колледжа. Девиантология. 2022; 6 (1): 3035. [Kozlov V.A., Tavinova N.A., Golenkov A.V. Predisposition to addictive behavior in students of medical college. Deviant Behavior (Russia). 2022; 6 (1): 30-35.] (In Russ) DOI: 10.32878/devi.22-6-01(10)-30-35
  • Catalano R.A., Goldman-Mellor S., Karasek D.A., et al. Collective optimism and selection against male twins in utero. Twin Res Hum Genet. 2020; 23 (1): 45-50. DOI: 10.1017/thg.2020.2
  • Gilfillan C.P., Robertson D.M., Burger H.G., Leoni M.A., Hurley V.A., Martin N.G. The control of ovulation in mothers of dizygotic twins. J Clin Endocrinol Metab. 1996; 81 (4): 1557-1562. DOI: 10.1210/jcem.81.4.8636367
  • Duffy D.L., Montgomery G.W., Hall J., Mayne C., Healey S.C., Brown J., Boomsma D.I., Martin N.G. Human twinning is not linked to the region of chromosome 4 syntenic with the sheep twinning gene FecB. Am J Med Genet. 2001; 100 (3): 182-186. DOI: 10.1002/ajmg.1255
  • Painter J.N., Willemsen G., Nyholt D., Hoekstra C., Duffy D.L., Henders A.K., Wallace L., Healey S., Cannon-Albright L.A., Skolnick M., Martin N.G., Boomsma D.I., Montgomery G.W. A genome wide linkage scan for dizygotic twinning in 525 families of mothers of dizygotic twins. Hum Reprod. 2010; 25 (6): 1569-1580. DOI: 10.1093/humrep/deq084
  • Mbarek H., van de Weijer M.P., van der Zee M.D., Ip H.F., Beck J.J., Abdellaoui A., Ehli E.A., Davies G.E., Baselmans B.M.L., Nivard M.G., Bartels M., de Geus E.J., Boomsma D.I. Biological insights into multiple birth: genetic findings from UK Biobank. Eur J Hum Genet. 2019; 27 (6): 970-979. DOI: 10.1038/s41431-019-0355-z
  • Lewkowitz A.K., López J.D., Keller M., Rosenbloom J.I., Macones G.A., Olsen M.A., Cahill A.G. Association between delivering live-born twins and acute psychiatric illness within 1 year of delivery. Am J Obstet Gynecol. 2021; 224 (3): 302.e1-302.e23. DOI: 10.1016/j.ajog.2020.09.005
  • White T.G. Folie simultanée in monozygotic twins. Can J Psychiatry. 1995; 40 (7): 418-420. DOI: 10.1177/070674379504000710
  • Too L.S., Spittal M.J., Bugeja L., Reifels L., Butterworth P., Pirkis J. The association between mental disorders and suicide: A systematic review and meta-analysis of record linkage studies. J Affect Disord. 2019; 259: 302-313. DOI: 10.1016/j.jad.2019.08.054
  • Nock M.K., Hwang I., Sampson N.A., Kessler R.C. Mental disorders, comorbidity and suicidal behavior: results from the National Comorbidity Survey Replication. Mol Psychiatry. 2010; 15 (8): 868-876. DOI: 10.1038/mp.2009.29
  • Orri M., Geoffroy M.C., Turecki G., et al. Contribution of genes and environment to the longitudinal association between childhood impulsive-aggression and suicidality in adolescence. J Child Psychol Psychiatry. 2020; 61 (6): 711-720. DOI: 10.1111/jcpp.13163
  • Krebs G., Mataix-Cols D., Rijsdijk F., et al. Concurrent and prospective associations of obsessive-compulsive symptoms with suicidality in young adults: A genetically-informative study. J Affect Disord. 2021; 281: 422-430. DOI: 10.1016/j.jad.2020.10.065
  • Wang M., Mather L., Svedberg P., Mittendorfer-Rutz E. Suicide attempt following sickness absence and disability pension due to common mental disorders: a prospective Swedish twin study. Soc Psychiatry Psychiatr Epidemiol. 2020; 55 (8): 1053-1060. DOI: 10.1007/s00127-019-01803-w
  • Roy A., Rylander G., Forslund K., Asberg M., Mazzanti C.M., Goldman D., Nielsen D.A. Excess tryptophan hydroxylase 17 779C allele in surviving cotwins of monozygotic twin suicide victims. Neuropsychobiology. 2001; 43 (4): 233-236. DOI: 10.1159/000054895
  • Brezo J., Klempan T., Turecki G. The genetics of suicide: a critical review of molecular studies. Psychiatr Clin North Am. 2008; 31 (2): 179-203. DOI: 10.1016/j.psc.2008.01.008
  • Li D., He L. Further clarification of the contribution of the tryptophan hydroxylase (TPH) gene to suicidal behavior using systematic allelic and genotypic meta-analyses. Hum Genet. 2006; 119 (3): 233-240. DOI: 10.1007/s00439-005-0113-x
  • Courtet P., Jollant F., Castelnau D., Buresi C., Malafosse A. Suicidal behavior: relationship between phenotype and serotonergic genotype. Am J Med Genet C Semin Med Genet. 2005; 133C (1): 25-33. DOI: 10.1002/ajmg.c.30043
  • Souery D., Oswald P., Linkowski P., Mendlewicz J. Molecular genetics in the analysis of suicide. Ann Med. 2003; 35 (3): 191-196. DOI: 10.1080/07853890310008242
  • Zouk H., McGirr A., Lebel V., Benkelfat C., Rouleau G., Turecki G. The effect of genetic variation of the serotonin 1B receptor gene on impulsive aggressive behavior and suicide. Am J Med Genet B Neuropsychiatr Genet. 2007; 144B (8): 996-1002. DOI: 10.1002/ajmg.b.30521
  • Ozalp E. Intihar Davrani^imn Genetigi [The genetics of suicidal behavior]. Turk Psikiyatri Derg. 2009 Spring; 20 (1): 85-93. (In Turkish)
  • Giegling I., Hartmann A.M., Möller H.J., Rujescu D. Anger- and aggression-related traits are associated with polymorphisms in the 5-HT-2A gene. J Affect Disord. 2006; 96 (1-2): 75-81. DOI: 10.1016/j.jad.2006.05.016
  • Anguelova M., Benkelfat C., Turecki G. A systematic review of association studies investigating genes coding for serotonin receptors and the serotonin transporter: II. Suicidal behavior. Mol Psychiatry. 2003; 8 (7): 646-653. DOI: 10.1038/sj.mp.4001336
  • Manuck S.B., Flory J.D., Ferrell R.E., Mann J.J., Muldoon M.F. A regulatory polymorphism of the monoamine oxidase-A gene may be associated with variability in aggression, impulsivity, and central nervous system serotonergic responsivity. Psychiatry Res. 2000 Jul 24; 95 (1): 9-23. DOI: 10.1016/s0165-1781(00)00162-1
  • Mann J.J., Arango V.A., Avenevoli S., Brent D.A., Champagne F.A., Clayton P., Currier D., Dougherty D.M., Haghighi F., Hodge S.E., Kleinman J., Lehner T., McMahon F., Moscicki E.K., Oquendo M.A., Pandey G.N., Pearson J., Stanley B., Terwilliger J., Wenzel A. Candidate endophenotypes for genetic studies of suicidal behavior. Biol Psychiatry. 2009; 65 (7): 556-563. DOI: 10.1016/j.biopsych.2008.11.021
  • Wasserman D., Geijer T., Rozanov V., Wasserman J. Suicide attempt and basic mechanisms in neural conduction: relationships to the SCN8A and VAMP4 genes. Am J Med Genet B Neuropsychiatr Genet. 2005; 133B (1): 116119. DOI: 10.1002/ajmg.b.30128
  • Tsai S.J., Hong C.J., Liou Y.J. Recent molecular genetic studies and methodological issues in suicide research. Prog Neuropsychopharmacol Biol Psychiatry. 2011; 35 (4): 809-817. DOI: 10.1016/j.pnpbp.2010.10.014
  • Perlis R.H., Huang J., Purcell S., Fava M., Rush A.J., Sullivan P.F., Hamilton S.P., McMahon F.J., Schulze T.G., Potash J.B., Zandi P.P., Willour V.L., Penninx B.W., Boomsma D.I., Vogelzangs N., Middeldorp C.M., Rietschel M., Nöthen M., Cichon S., Gurling H., Bass N., McQuillin A., Hamshere M. Wellcome Trust Case Control Consortium Bipolar Disorder Group; Craddock N., Sklar P., Smoller J.W. Genome-wide association study of suicide attempts in mood disorder patients. Am J Psychiatry. 2010; 167 (12): 1499-1507. DOI: 10.1176/appi.ajp.2010.10040541. Erratum in: Am J Psychiatry. 2011; 168 (1): 100.
  • Schulze T., Thomas G., Galfalvy H., Zalsman G., Huang Y.Y., Murphy L., Rosoklija G., Dwork A.J., Haghighi F., Arango V., Mann J.J. A pilot genome wide association and gene expression array study of suicide with and without major depression. World J Biol Psychiatry. 2013; 14 (8): 574-582. DOI: 10.3109/15622975.2011.597875
  • Galfalvy H., Zalsman G., Huang Y.Y., Murphy L., Rosoklija G., Dwork A.J., Haghighi F., Arango V., Mann J.J. A pilot genome wide association and gene expression array study of suicide with and without major depression. World J Biol Psychiatry. 2013; 14 (8): 574-582. DOI: 10.3109/15622975.2011.597875
  • Gupta G., Deval R., Mishra A., Upadhyay S., Singh P.K., Rao V.R. Re-testing reported significant SNPs related to suicide in a historical high-risk isolated population from north east India. Hereditas. 2020; 157 (1): 31. DOI: 10.1186/s41065-020-00144-y
  • Verberne T.J. A developmental model of vulnerability to suicide: consistency with some recurrent findings. Psychol Rep. 2001; 89 (2): 217-226. DOI: 10.2466/pr0.2001.89.2.217
Еще
Статья научная
SciUp 2024 © 2024 ©