The numerical-and-sized composition of the muscular fibers of the anterior tibial muscle for regeneration of canine crossed sciatic nerve under the condition of neutral and distraction osteosynthesis

The changes of numerical-and-sized composition of the muscular fibers of the anterior tibial muscle have been studied in mongrel dogs under different conditions of sciatic nerve regeneration: after its crossing and microsurgical suturing (gorup I), in case of neurotomy combined with femoral osteotomy under neutral osteosynthesis (group II) and distraction osteosynthesis (group III). In group I by 4 months after surgery the distribution of muscle fibers by diameter is comparable with anintact muscle. In group II the asymmetry of distribution histograms demonstrates the remaining atrophy of muscular fibers in the muscle of the limb operated and their compensatory hypertrophy in the contralateral limb. The changes in endoneurium volumetric part, those in the numerical density of muscle fibers and microvessels of the anterior tibial muscle in the animals of series III comparing with the intact ones show vascularization increase and the intensive plastic reorganization of muscle fibers in the experiments where distraction osteosynthesis is used.