Comparative study on free radical ameliorating potential of stem and the leaf extracts of plectranthus amboinicus
Автор: Vijayanand S., Sri Ram Thiruvengadam, Malathi R.
Журнал: Журнал стресс-физиологии и биохимии @jspb
Статья в выпуске: 1 т.19, 2023 года.
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The Plectranthus amboinicus is known for its medicinal properties. The extracts from this plant material are used to treat different diseases which include cold, respiratory disorders, digestive problems, skin infections, cough, chronic asthma, bronchitis, hiccups, etc. The present study aimed to compare and evaluate the antioxidant property of two aerial parts of the plant, the stem and the leaf extracts of Plectranthus amboinicus . The different type of extracts was prepared with fresh leaves, fresh stem and dried leaves, with methanol as the solvent for extraction. The antioxidant potential of each extract was checked and the result obtained showed the fresh stem extract had the highest antioxidant activity. The study result shows that the methanolic extracts of dried leaves have Tannins, flavonoids, phenol and reducing sugars. The methanolic extract of fresh leaves and fresh stem extracts showed the presence of Tannins, flavonoids, quinone, steroids, phenols and reducing sugars. The phenolic content of the methanolic extract of the stem is high compared to fresh and dried leaves. The anti-oxidant potentials were assayed through the FRAP, FTC and TBA assays, the results showed that the free radical scavenging property of the methanolic extract of the stem is high compared to the fresh and dried leaves. The methanolic stem extract has high phenolic content and also shows high free radical scavenging properties than the methanolic extract of fresh and dried leaves.
Plectranthus amboinicus, frap, ftc, anti-oxidant activity, phenolic content, phytochemicals
Короткий адрес: https://sciup.org/143179370
IDR: 143179370
Список литературы Comparative study on free radical ameliorating potential of stem and the leaf extracts of plectranthus amboinicus
- Achour, S., Chebaibi, M., Essabouni, H., Bourhia, M., Ouahmane, L., Mohammad Salamatullah, A.....& Giesy, J. P. (2022). Ethnobotanical Study of Medicinal Plants Used as Therapeutic Agents to Manage Diseases of Humans. Evidence-Based Complementary and Alternative Medicine, 2022. Article ID 4104772, 8. https://doi.org/10.1155/2022/4104772
- Arumugam, G., Swamy, M. K., & Sinniah, U. R. (2016). Plectranthus amboinicus (Lour.) Spreng: botanical, phytochemical, pharmacological and nutritional significance. Molecules, 21(4), 369.
- Bors, W., & Michel, C. (2002). Chemistry of the antioxidant effect of polyphenols. Annals of the New York Academy of Sciences, 957(1), 57-69. doi:10.1111/j.1749-6632.2002.tb02905.x
- Esmaeilbeig, M., Kouhpayeh, S. A., & Amirghofran, Z. (2015). An investigation of the growth inhibitory capacity of several medicinal plants from Iran on tumor cell lines. Iranian journal of cancer prevention, 8(5). e4032.
- Greenwell, M., & Rahman, P. K. S. M. (2015). Medicinal plants: their use in anticancer treatment. International journal of pharmaceutical sciences and research, 6(10), 4103-4112.
- Laldingliani, T. B. C., Thangjam, N. M., Zomuanawma, R., Bawitlung, L., Pal, A., & Kumar, A. (2022). Ethnomedicinal study of medicinal plants used by Mizo tribes in Champhai district of Mizoram, India. Journal of Ethnobiology and Ethnomedicine, 18(1), 1-29.
- Mengistu, D. K., Mohammed, J. N., Kidane, Y. G., & Fadda, C. (2022). Diversity and Traditional Use Knowledge of Medicinal Plants among Communities in the South and South-Eastern Zones of the Tigray Region, Ethiopia. Diversity, 14(4), 306.
- Mothana, R. A., Khaled, J. M., El-Gamal, A. A., Noman, O. M., Kumar, A., Alajmi, M. F.....& Al-Said, M. S. (2019). Comparative evaluation of cytotoxic, antimicrobial and antioxidant activities of the crude extracts of three Plectranthus species grown in Saudi Arabia. Saudi Pharmaceutical Journal, 27(2), 162-170.
- Nair, M. S., Soren, K., Singh, V., & Boro, B. (2016). Anticancer activity of fruit and leaf extracts of Averrhoa bilimbi on mcf-7 human breast cancer cell lines: a preliminary study. Austin J Pharmacol Ther, 4(2), 1082.
- Negi, P. S., Chauhan, A. S., Sadia, G. A., Rohinishree, Y. S., & Ramteke, R. S. (2005). Antioxidant and antibacterial activities of various seabuckthorn (Hippophae rhamnoides L.) seed extracts. Food Chemistry, 92(1), 119-124. doi:10.1016/j.foodchem.2004.07.009
- Nguyen, V. T., Nguyen, M. T., Nguyen, N. Q., & Truc, T. T. (2020, December). Phytochemical screening, antioxidant activities, total phenolics and flavonoids content of leaves from persicaria odorata polygonaceae. In IOP Conference Series: Materials Science and Engineering (Vol. 991, No. 1, p. 012029). IOP Publishing.
- Pillai, P. G., Suresh, P., Gitanjali, M., (2013) Induction of Apoptosis in Human Colon Cancer Cells by Methanol Fraction of Leaves of Plectranthus amboinicus (Lour) Spreng. International Journal for Pharmaceutical Research Scholars (IJPRS), 2(3), 74 - 82.
- Prasathkumar, M., Anisha, S., Dhrisya, C., Becky, R., & Sadhasivam, S. (2021). Therapeutic and pharmacological efficacy of selective Indian medicinal plants-a review. Phytomedicine Plus, 1(2), 100029. ISSN 2667-0313, https://doi.org/10.1016/j.phyplu.2021.100029.
- Ramani, S., Basak, S., Puneeth, S., Mahato, K., & Malathi, R. (2021). Anti Hemolytic Activity of Rutin incase of Phenyl Hydrazine induced Hemolysis. Current Trends in Biotechnology and Pharmacy, 15(5), 467-470.https://doi.org/10.5530/ctbp.2021.3s.41
- Rodrigues, F. F., Boligon, A. A., Menezes, I. R., Galvao-Rodrigues, F. F., Salazas, G. J., Nonato, C. F.....& Barros, A. R. (2021). HPLC/DAD, Antibacterial and Antioxidant Activities of Plectranthus Species (Lamiaceae) Combined with the Chemometric Calculations. Molecules, 26(24), 7665.
- Sahu, D., Bolleddu, R., Das, M., Das, D., Mandal, T. K., Debnath, S. K..... & Prasad, P. V. V. (2022).
- Pharmacognostical and Phytochemical Studies of Leaves of Plectranthus amboinicus (Lour.) Spreng. (Parnayavani). Research Journal of Pharmacy and Technology, 15(2), 717-722.
- Soni, A., & Sosa, S. (2013). Phytochemical analysis and free radical scavenging potential of herbal and medicinal plant extracts. Journal of Pharmacognosy and phytochemistry, 2(4), 22-29.
