COVID-19: application of intra-pulmonary injection of hydrogen peroxide solution eliminates hypoxia and normalizes respiratory biomechanics in respiratory obstruction

Автор: Urakov A.L., Urakova N.A.

Журнал: Российский журнал биомеханики @journal-biomech

Статья в выпуске: 4 (94) т.25, 2021 года.

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Severe non-specific pneumonia is complicated by airway obstruction, which is caused by swelling of the mucous membranes of the airways and blockage of their mucus, pus and thick sputum with streaks of blood. A particularly significant decrease in airiness occurs in the peripheral regions of the lungs. This is why the air introduced through the upper respiratory tract does not reach the alveoli, primarily in the peripheral areas of the lungs. Under these conditions, traditional ventilation of the lungs provides a back-and-forth movement of air only in the trachea, large and small bronchi, since only these areas of the respiratory tract remain unclogged by mucus and pus. But these areas of the respiratory tract do not provide effective oxygenation of the patient's blood. Therefore, conventional artificial lung ventilation (ventilator) cannot normalize the biomechanics of respiration until the elimination of respiratory obstruction. Therefore, in the case of respiratory biomechanics depression caused by respiratory obstruction, it is currently customary to oxygenate blood by extrapulmonary route - using extracorporeal membrane oxygenation (ECMO). However, ECMO is a very dangerous and poorly available method of treatment. Therefore, to save the lives of patients with severe hypoxia, it is proposed to urgently restore pulmonary blood oxygenation by oxygenating the lungs by injecting a solution of pus solvent into the peripheral areas of the lungs. At the same time, intra-pulmonary injection of an alkaline peroxide solvent of pus provides an immediate appearance of oxygen gas in the peripheral respiratory tract, since pus and blood veins contain the enzyme catalase, which immediately decomposes hydrogen peroxide into oxygen gas and water. In this case, mucus, pus and sputum with streaks of blood immediately turn into oxygen foam, which is easily removed through the upper respiratory tract to the outside.

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Respiratory obstruction, respiratory biomechanics, intra-pulmonary injection, pus solvent, hydrogen peroxide

Короткий адрес: https://sciup.org/146282400

IDR: 146282400   |   DOI: 10.15593/RZhBiomeh/2021.4.06

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