BPH: predictors of disease progression and transition from conservative to surgical treatment

Introduction. Some patients with benign prostatic hyperplasia (BPH) do not respond to treatment or the disease progresses during conservative treatment. It seems relevant to identify significant predictors of BPH progression and transition from conservative to surgical treatment. экспериментальная и клиническая урология № 1 2025 www.ecuro.ru Materials and methods. The review was conducted using the databases PubMed, Embase, Cochrane Library, Scientific Electronic Library eLlibrary.ru and the Russian Science Citation Index. The database search was carried out using the following keywords in English and their analogues in Russian: «benign prostatic hyperplasia», «benign prostatic obstruction», «bladder outlet obstruction», «lower urinary tract symptoms», «medical therapy», «phar-macotherapy», «alpha-blockers», «5-alpha-reductase inhibitors», «predictors of treatment failure», «predictors of benign prostatic hyperplasia progression», «intravesical prostatic protrusion». There were no restrictions on years of publication. At the first stage, 695 sources were found, 58 articles were selected for inclusion in the review.