Diagnostics and treatment of biliary duct carcinoma

Sixty-six patients with biliary ducts carcinoma were treated: 41 with primary tumors of bile ducts and 25 with metastatic lesions of hepatic portal lymph nodes. The main method of radiological diagnostics was sonographic tomography. Morphological diagnostics was made after cytological examination of bile and transcutaneous puncture biopsy. Hepatic insufficiency was detected in all patients with biliary ducts carcinoma with the syndrome of jaundice. In those cases transcutaneous, trashepatic endobiliarty decompressive interventions effectively liquidated cholestasis with minimal risk of complications and of death, caused by hepatic insufficiency and intervention itself. 3 patients with primary cancer of bile ducts received combined treatment, 30 such patients got radiation therapy; 20 patients with metastatic tumors underwent chemotherapy and radiation therapy. Mean survival, 3-year survival after radiation therapy or chemoradiotharapy were 22,7 ± 4,2 months and 8,3 ± 3,8 %, respectively. The mean survival of patients with metastatic lesions of hepatic portal lymph nodes was 24,5 ± 4,3 months