The dynamics of 0,1 Hz-component of heart rate variability at patients with arterial hypertension at treatment by fosinopril and atenolol

Aim: to study dynamics of the 0,1Hz-component of the heart rate variability (HRV) spectrum in patients with arterial hypertension taking fosinopril and atenolol. 49 patients with hypertension were enrolled (age - 46±7 years). Fosinopril and atenolol were administered consequently. The power of 0,1Hz-component of the HRV spectrum was assessed during a passive orthostatic test. Results: In patients taking fosinopril and atenolol comparable decrease of blood pressure was observed. Atenolol caused reliable decrease of a heart rate during orthostatic test. The power dynamics of 0,1Hzcomponent was comparable in patients taking fosinopril and atenolol. Conclusion: fosinopril and atenolol influenced similar on 0,1-Hz mechanisms of vegetative heart control system.