Dynamics of hormones of the pituitary-thireoid system and EEG of brain activity in high-mountain residents

The article presents an analysis of the results of studies to determine the functional state of the pituitary-thyroid system and to identify their relationship with the neurodynamic EEG parameters of the brain in mountainous conditions (2800 m). The results of enzyme-linked immunosorbent assays of blood in mountain dwellers indicate functional activation (according to average values of T4 and T3 levels) of the peripheral link and compensatory calmness of the central link (relatively low levels of TSH) of the pituitary-thyroid system. A decrease in TSH secretion at a normal level of thyroxine indicates a trend towards a decrease in the functional state of the thyroid gland, which confirms the presence of adaptive changes in the body of mountaineers. At the same time, the detected normal (or with a slight deviation in one direction or another) thyroxine level does not at all contradict the general pattern, because reflects the variability inherent in biological phenomena, due to the individual characteristics of the organism, and the dependence of the studied indicator on factors other than hypoxic factors. Due to the high tension of the functioning of the central nervous system in high altitude conditions, there is a peculiar shift in the EEG parameters towards a decrease in the alpha rhythm and an increase in the theta rhythm of tension, which causes a noticeable redistribution of typological groups. The type of CMR of the brain on the EEG has close functional relationships with the level of TSH, and also has a weak functional relationship with the levels of thyroid hormones.