Dynamics of immunological activation processes under new method of medical rehabilitation

The modern innovative method of medical rehabilitation is based on intensive equally accelerated vibrostimulation of the human proprioceptive system. The purpose of this paper is to examine and analyze the expression of activation antigens in immunocompetent cells under a new method of medical neuromuscular rehabilitation. Materials and Methods. The Power Plate was used for a long program (6 months) of neuromuscular vibrostimulation. The authors examined 40 elderly women. Flow laser cytometry was used for phenotyping of immunocompetent cells. Results. The dynamics of expression of an early activation marker did not demonstrate significant changes within 6 months. In the experimental group, the authors observed a decrease in the content of cells with late activation antigens in 12 weeks and the subsequent incremental recovery up to the end of the trial. In the control group negative dynamics of HLA-DR+ antigen expression was revealed. Conclusion. The number of lymphocytes expressing the CD2+ and HLA-DR+ markers demonstrated the objective safety of the long-term program of neuromuscular rehabilitation for the activation processes in the human immune system, particularly in elderly people. It is recommended to use the new modern method of neuromuscular stimulation, not only in the sport-of-records physiology, but also in practical rehabilitation, gerontology and clinical physiology.