Dynamics of cellular immunity indicators in patients with parallel pelvic injuries

Goal. To study changes in cellular immunity indicators in patients with penetrating gunshot wounds of the pelvis in the immediate postoperative period. Materials and methods. The study included 40 female patients from the civilian population who were treated for penetrating gunshot wounds of the pelvis received as a result of local hostilities. All patients were female, the average age was 36±4 years. Two clinical groups were formed. In the first (A), the wounded were selected in the number of 20 (50%) people, whose time interval did not exceed 60 minutes, in the second (B) — 20 (50%) wounded, whose time interval exceeded 60 minutes. To achieve this goal, a study of laboratory parameters characterizing cellular immunity was conducted: the total number of leukocytes in peripheral blood, lymphocytes (%), determining changes in subpopulations of both T-lymphocytes and B-lymphocytes. The number of mature T lymphocytes (CD3+); T helper cells (CD4+); cytotoxic T cells (CD8+); natural killers (CD16+); B cells (CD20+) was calculated. Results. As a result of the study, it was found that changes in the cellular link of the immune system in gunshot wounds of the pelvis depend on the time elapsed from the moment of injury to the beginning of surgical intervention. At the same time, if surgical intervention was performed up to one hour from the moment of injury, changes in the subjects occurred later and recovered earlier compared to the group of wounded who underwent surgical intervention later than one hour from the moment of injury.