Rationale for studying the mechanics of heart diastole, pulse wave and expansion of the internal organs which do not have inherent skeleton

The objectives of the work were to determine the rationale of the conceptual phases in studying the complex motion mechanics of the internal organs which do not have inherent skeleton (lungs, bronchi, heart, blood vessels, and the organs of the digestive system) and to present the results of completion of the first study phase for the lungs providing evidence of their autonomous inspiratory and expiratory mechanical activity. Apart from the lungs, an ability of other internal organs to actively expand remains not proved. The second conceptual phase involves identification of a source of mechanical energy, produced by the lungs, and elucidation of the morphofunctional characteristics of this source. The third phase consists of a verification of the hypothesis about the existence of the functional skeleton of the internal organs and provides morphological and functional characterization of this entity. The fourth phase involves examination of the approaches for a pharmacological modulation of the entity responsible for the internal organ expansion. Completion of all four study phases requires development of new technologies. The methodic and, uppermost, methodological problems in studying the mechanics of the internal organs represent essentials of new horizons in Physiology.