Bilateral acute generalized uveitis with Vogt-Koyanagi-Harada syndrome

This study presents a case of bilateral generalized uveitis with exudative retinal detachment and Vogt- Koyanagi-Harada syndrome with a severe fulminant course in 27 year-old man with underlying neurological manifestations and hearing loss. The delayed diagnosis of the disease led to the rapid development of the late stage of uveitis with depigmentation of the fundus in the form of the "setting sun", persistent reduction of vision and complications with development of cataract, ophthalmic hypertension, epiretinal synechia and relapses. High-dose corticosteroids and immunosuppressive therapy allowed to achieve a positive effect and partially restore visual functions. Uveitis with a symmetrical lesion in both eyes is often an ophthalmological manifestation of systemic diseases. When it develops in individuals with darker skin pigmentation it is necessary to bear in mind the Vogt- Koyanagi-Harad syndrome.