Risk factors of obstructive complications after endoscopic treatment for vesicoureteral reflux using polyalcohol-polyacrylate copolymer: multicenter study

Background: Experience in using polyalcohol-polyacrylate copolymer (PPC) demonstrates not only its high efficacy but also higher risk of obstructive complications (OC) associated with its use when compared with other implants. Identification and further study of risk factors for OC may improve safety of PPC use. Materials and methods: A retrospective analysis of medical data of 774 patients, who underwent treatment using PPC in 5 clinics, was performed. Patients were divided into 2 groups. Group I included 733 children without OC, among them 435 (59,3%) girls and 298 (40,7%) boys. Median age was 41 months [18,0;81,0]. STING technique was used in 668 (91.1%) children, HIT was used in 65(8,9%) patients. Group II included 41(5%) patients with OC, median age was 21,5 months [12,0;43,0]; there were 27 (65.9%) boys, and 14 (34.1%) girls. STING technique was used in 18 (41.5%) patients, while HIT technique was used in 23 (58,5%) children. Renal ultrasound was performed 1 day, 1 month, 3, 6 and 12 months after the surgery, and then every 6 months, while voiding cystourethrogram was performed 4-5 months after endoscopic treatment...