Risk factors of development of cholestatic hepatosis during pregnancy

A total of 172 pregnant women aged 15 to 47 years were examined. There was an increase in the number of patients with cholestatic hepatosis of pregnant women (HPW) from 1.1% to 1.6%. In women with HPW, hepatobiliary diseases are significantly more frequent: chronic viral hepatitis B and C (15%), chronic cholecystitis (14.2%), cholelithiasis (12.4%). HPW in 14.2% of women was in previous pregnancies. Thrombophilia, anemia and gestational hypertension can also contribute to the development of HPW.