Survival rate impact factors in patients treated by hemodialysis for chronic kidney disease

Identification of lethal outcome predictors is of great importance for the forecast of possible treatment outcome in case of hemodialysis and a choice of optimum correction tactics in patients treated by dialysis. It is also essential in prophylaxis and control of disorders prior to the replacement kidney therapy. The purpose of the study was to clarify their influence on the survival rate of the invalid mineral and bone violations revealed in the patients treated by hemodialysis. The retrospective analysis included 508 patients treated by hemodialysis as a replacement kidney therapy. A group of patients with lethal outcome (162 persons) was allocated from the control group of patients. The duration of hemodialysis treatment ranged from 3 months to 21 year (on average 4,5 ± 0,4 years). It was established that the annual number of patients with mineral and bone disorders in chronic kidney disease and receiving treatment by hemodialysis raged from 74,4 to 85,6 %. Thus, the average level of phosphorus in the studied population ranged from 2,16 to 2,95 mmol/l, the general calcium - from 2,22 to 2,34 mmol/l. It is shown that the high risk of lethal outcome in the group of examined patients was observed at phosphorus level 3,0 mmol/l (r = 0,09), PTG 2,5 mmol/l. The formula of prognostic lethal outcome calculation, incorporating duration of treatment by hemodialysis for any specific patient, is offered.