Фармацевтические соединения на основе азотсодержащих гетероциклов - новый класс загрязнителей окружающей среды (обзор)

Автор: Мухутдинова А.Н., Рычкова М.И., Тюмина Е.А., Вихарева Е.В.

Журнал: Вестник Пермского университета. Серия: Биология @vestnik-psu-bio

Статья в выпуске: 1, 2015 года.

Бесплатный доступ

Фармполлютанты - высокостабильные соединения с разнообразной химической структурой и выраженной биологической активностью. Они обнаруживаются в почве, донных осадках водоемов, сточных, грунтовых водах и даже питьевой воде. Неконтролируемое поступление лекарственных средств в открытые экосистемы потенциально опасно, так как последствия их воздействия на живые организмы могут быть непредсказуемы. Среди фармполлютантов, детектируемых в окружающей среде, большим числом представлены азотсодержащие гетероциклические соединения. Приоритетными направлениями исследований являются изучение процессов, происходящих с фармполлютантами в окружающей среде, поиск эффективных способов нейтрализации данных опасных соединений, изучение степени их биодоступности, токсического действия новых соединений на живые организмы, в том числе микроорганизмы-деструкторы, выяснение взаимосвязи систематической принадлежности микроорганизмов и их способности деградировать лекарственные вещества.

Еще

Фармполлютанты, токсическое воздействие, биологическая деструкция

Короткий адрес: https://sciup.org/147204711

IDR: 147204711

Список литературы Фармацевтические соединения на основе азотсодержащих гетероциклов - новый класс загрязнителей окружающей среды (обзор)

Баренбойм Г.М., Чиганова М.А. Загрязнение поверхностных и сточных вод лекарственными препаратами//Вода: химия и экология. 2012. № 10. С. 40-46
Гетьман М.А., Наркевич И.А. Лекарственные средства в окружающей среде//Ремедиум. 2013. № 2. С. 50-54
Гуринович А.Д., Житенёв Б.Н., Воронович Н.В. Очистка природных вод от фармацевтических препаратов методом окисления//Вестник Брестского государственного технического университета. 2012. № 2. С. 21-27
Демушкин В.П., Жаворонкова Е.В., Хаспеков Л.Г. Влияние дротаверина гидрохлорида на жизнеспособность культивируемых клеток-зерен мозжечка крыс//Бюллетень экспериментальной биологии и медицины. 2011. Т. 152, № 10. С. 425-427
Предозонирование -как средство интенсификации процессов биологической очистки сточных вод/А.А. Цхе //Политематический сетевой электронный научный журнал Кубанского государственного аграрного университета (Научный журнал КубГАУ). 2013. № 87. URL: http://ej.kubagro.ru/2013/03/pdf/38.pdf. (дата обращения: 18.07.2014)
A Review on pharma pollution/K. Shalini //International Journal of Pharm Tech Research. 2010. Vol. 2, № 4. P. 2265-2270
Antibiotic uptake by plants from soil fertilized with animal manure/К. Kumar //Journal of Environmental Quality. 2005. Vol. 34. P. 20822085
Antibiotics in the offshore waters of the Bohai Sea and the Yellow sea in China: occurrence, distribution and ecological risks/R. Zhang //Environmental Pollution. 2013. Vol. 174. P. 71-77
Bedner M., Maccrehan W. Transformation of acetaminophen by chlorination produces the toxicants 1,4-benzoquinone and N-acetyl-p-benzoquinone//Environmental Science and Technology. 2006. Vol. 40. P. 516-522
Bennet G., Fram M., Belitz K. Status and understanding of groundwater Quality in the Klamath Mountains study Unit, 2010: California GAMA Priority Basin Project//Water Boards, 2014. 70 pp
Benotti M.J., Brownawell B.J. Microbial degradation of pharmaceuticals in estuarine and coastal sea-water//Environmental Pollution. 2009. Vol. 157. P. 994-1002
Bessems J.G., Vermeulen N.P. Paracetamol (aceta-minophen)-induced toxicity: molecular and biochemical mechanisms, analogues and protective approaches//Critical Reviews in Toxicology. 2001. Vol. 31, № 1. P. 55-138
Bioconversion of codeine to semi-synthetic opiate derivatives by the cyanobacterium Nostoc muscorum/S. Niknam //World Journal of Microbiology and Biotechnology. 2010. Vol. 26. P. 119123
Biodegradation of bulk drug industrial effluents from microbial/P.A. Ajay Babu //Journal of Scientific and Industrial Research. 1999. Vol. 58. P. 431-435
Biodegradation of drotaverine hydrochloride by free and immobilized cells of Rhodococcus rhodochrous IEGM 608/I.B. Ivshina //World Journal of Microbiology and Biotechnology. 2012. Vol. 28. P. 2997-3006
Biodegradation of papaverine and harmaline with the Basidiomyectous Pharierochaese chrysosporium/L. Zhao //5th International Conference on Bioinformatics and Biomedical Engineering. 2011. P. 1-4
Calisto V., Esteves V. Psychiatric pharmaceuticals in the environment//Chemosphere. 2009. Vol. 77. P. 1257-1274
Carucci A., Coppai G., Piredda M. Biodegradability and toxicity of pharmaceuticals in biological wastewater treatment plants//Journal of Environmental Science and Health Part A. 2006. Vol. 41. P. 1831-1842
Celiz M.D., Tso J., Aga D.S. Pharmaceutical metabolites in the environment: analytical challenges and ecological risks//Environmental Toxicology and Chemistry. 2009. Vol. 28, № 12. P. 2473-2484
Characterization and biodegradation kinetics of a new cold-adapted carbamazepine-degrading bacterium Pseudomonas sp. CBZ-4/A. Li //Journal of Environmental Sciences. 2013. Vol. 25, № 11. P. 2281-2290
Chevre N. Pharmaceuticals in surface waters: sources, behavior, ecological risk, and possible solutions. Case study of Lake Geneva, Switzerland//WIREs Water. 2014. Vol. 1. P. 69-86
Daughton C.G. Illicit Drugs: Contaminants in the environment and utility in forensic epidemiology//Reviews of Environmental Contamination and Toxicology/Ed. D.M. Whitacre. Springer, 2011. P. 59-110
De Lorenzo M.E., Fleming J. Individual and mixture effects of selected pharmaceuticals and personal care products on the marine phytoplankton species Dunaliella tertiolecta//Archives of Environmental Contamination and Toxicology. 2008. Vol. 54, № 2.P. 203-210
Degradation of 40 selected pharmaceuticals by UV/H2O2/B.A. Wols //Water Research. 2013. Vol. 47, № 15.P. 5876-5888
Degradation of carbamazepine by Trametes versi-color in an air pulsed fluidized bed bioreactor and identification of intermediates/A. Jelic //Water Research. 2012. Vol. 46, № 4. P. 955-964
Degradation of the recalcitrant pharmaceuticals car-bamazepine and 17a-ethiniylestradiol by ligni-nolytic fungi/I.J.S. Santos //Chemical Engineering Transactions. 2012. Vol. 27. 16 pp
Determination of polar pharmaceuticals in sewage water of Greece by gas chromatography -mass spectrometry/V. Koutsouba //Chemos-phere. 2003. Vol. 51, № 2. P. 69-75
Drotaverine hydrochloride degradation using cyst-like dormant cells of Rhodococcus ruber/I.B. Ivshina //Current Microbiology. 2015. Vol. 70. P. 304-307
Du L., Liu W. Occurrence, fate and ecotoxicity of antibiotics in agro-ecosystems. A review//Agronomy for Sustainable Development. 2012. Vol. 32. Р. 309-327
Duca G., Boldescu V. Pharmaceuticals and personal care products in the environment//The role of ecological chemistry in pollution research and sustainable development/Eds A.M. Bahadir, G. Duca. Dordrecht, Netherlands, 2009: Springer Science and Business Media B.V. P. 27-35
Endreffy E., Boda D. Effect of drugs used in obstetrics on the constriction by oxygen of the ductus ar-teriosus of the rabbit fetus//Acta Paediatrica Hungarica. 1983. Vol. 24, № 3. P. 281-286
Fate of selected pharmaceuticals and personal care products after secondary wastewater treatment processes in Taiwan/A.Y.-C. Lin //Water Science and Technology. 2010. Vol. 62, № 10. P. 2450-2458
From multi -residue screening to target analysis of pharmaceuticals in water: development of a new approach based on magnetio sector mass spec-trometry and application in the Nairobi River basin, Kenya/K.O. K'oreje //Science of the Total Environment. 2012. Vol. 437. P. 153-164
Gorsalitz E.K. Comparative removal of pharmaceuticals and antimicrobials in conventional and constructed wetland wastewater treatment in cold climate: Master of Science thesis/Emily Kristine Gorsalitz. Iowa, 2012. 43 рp
Hauer B., Haase-Ashoff K., Lingens F. Papaverine deagradation with papaverine mutants of a No-cardia sp.//Hoppe-Seyler's Zeitschrift fur Physiologische Chemie. 1982. Vol. 363. P. 499-
Heberer T. From municipal sewage to drinking water: fate and removal of pharmaceutical residues in the aquatic environment in urban areas//Water Science and Technology. 2002. Vol. 46. Р. 81-88
Ingerslev F., Halling-Sorensen B. Biodegradability of metronidazole, olaquindox, and tylosin and formation of tylosin degradation products in aerobic soil-manure slurries//Ecotoxicology and Environmental Safety. 2001. Vol. 48, № 3. P. 311320
Jiemba P.K. Excretion and ecotoxicity of pharmaceutical and personal care products in the environment//Ecotoxicity and Enviromental Safety. 2006. Vol. 63. P. 113-130
Kunz D.A., Reddy G.S., Vatvrars A. Identification of transformation products arising from oxidation of codeine by Streptomyces griseus//Applied and Environmental Microbiology. 1985. Vol. 50, № 4. P. 831-836
Low biodegradability of fluoxetine HCl, diazepam and their human metabolites in sewage sludge-amended soil/C.H. Redshaw //Journal Soil Sediments. 2008. Vol. 8. Р. 217-230
Madyastha K.M., Reddy G.V.B., Sridhar G. Transformations of morphine, codeine and their analogs by Bacollus sp.//Indian Journal of Chemistry. Sect. B. 1998. Vol. 8, № 37. P. 749-753
Mompelat S., Le Bot B., Thomas O. Occurrence and fate of pharmaceutical products and by-products, from resource to drinking water//Environment International. 2009. Vol. 35, № 5. P. 803-814
Monteiro S.C., Boxall A.B.A. Pharmaceuticals and personal care products in the environment. Factors affecting the degradation of pharmaceuticals in agricultural soils//Environmental Toxicology and Chemistry. 2009. Vol. 28, № 12. P. 25462554
Narvaez Jh., Jimenez C.C. Pharmaceutical products in the environment: sources, effects and risks//Vitae, Revista de la facultad de quimica farmaceu-tica 2012. Vol. 19, № 1. P.93-108
Occurrence and fate of pharmaceutically active compounds in the environment a case study: Hoje river in Sweden/D. Bendz //Journal of Hazardous Materials. 2005. Vol. 122. P. 195-204
Pharmaceutical and personal care products in the somes river Basin, Romania/Z. Moldovan //Proceedings of the Swiss-Romanian Research Programme on Environmental Science and Technology. 2008. Vol. 14, № 1. Р. 49-56
Pharmaceutical chemicals and endocrine disrupters in municipal wastewater in Tokyo and their removal during activated sludge treatment/N. Nakada //Water Research. 2006. Vol. 40, № 17. Р. 3297-3303
Pharmaceuticals and personal care products (PPCPs) in surface and treated waters of Louisiana, USA and Ontario, Canada/G.R. Boyd //The Science of the Total Environment. 2003. Vol. 311, № 13. P. 135-149
Pharmaceuticals and personal care products in the aquatic environment in China: A review/Q. Bu //Journal of Hazardous Materials. 2013. Vol. 262. P. 189-211
Pharmaceuticals in the environment in Italy: causes, occurrence, effects and control/E. Zuccato //Environmental Science and Pollution Research. 2006. Vol. 13, № 1. P. 15-21
Pharmaceuticals, hormones, and other organic waste-water contaminants in U.S. streams, 1999-2000: A national reconnaissance/D.W. Kolpin //Environmental Science & Technology. 2002. Vol. 36, № 6. P. 1202-1211
Pollution pathways of pharmaceutical residues in the aquatic environment on the Island of Mallorca, Spain/C. Rodriguez-Navas //Archives of Environmental Contamination and Toxicology. 2013. Vol. 65. P. 56-66
Preliminary investigation on the environmental occurrence and effects of antibiotics used in aquacul ture in Italy/G.M. Lalumera //Chemosphere. 2004. Vol. 54. P. 661-668
Presence of fluoroquinolones and sulfonamides in urban sewage sludge and their degradation as a result of composting/M. Lillenberg //International Journal of Environmental Science. 2010. Vol. 7, № 2. P. 307-312
Primary biodegradation of veterinary antibiotics in aerobic and anaerobic surface water simulation systems/F. Ingerslev //Chemosphere. 2001. Vol. 44, № 4. P. 865-872
Quintana J., Reemtsma T. Sensitive determination of acidic drugs and triclosan in surface and wastewa-ter by ion-pair reverse-phase liquid chromatogra-phy/tandem mass spectrometry//Rapid Communications in Mass Spectrometry. 2004. Vol. 18. P. 765-774
Radjenovic J., Petrovic M., Barcelo D. Analysis of pharmaceuticals in wastewater and removal using a membrane bioreactor//Analytical and Bioana-lytical Chemistry. 2007. Vol. 387. P. 1365-1377
Removal and transformation of pharmaceuticals in wastewater treatment plants and constructed wetlands/E. Lee //Drinking Water Engineering and Science. 2013. Vol. 6. P. 89-98
Review of the occurrence of anti-infectives in contaminated wastewaters and natural and drinking waters/P.A. Segura //Environmental Health Perspective. 2009. Vol. 117, № 5. Р. 675684
Richardson M.L., Bowron J. The fate of pharmaceutical chemicals in the aquatic environment//Journal of Pharmacy and Pharmacology. 1985. Vol. 37, № 1. P. 1-12
Robinson A.A., Belden J.B., Lydy M.J. Toxicity of fluoroquinolone antibiotics to aquatic organisms//Environmental Toxicology and Chemistry. 2005. Vol. 24, № 2. P. 423-430
Singh P., Rani B., Maheshwari R. Pharmaceutical pollution: A short communication//International Journal of Pharmacy and Biological Sciences. 2011. Vol. 1, № 2. Р. 26-30
Snyder S.A., Benotti M.J. Endocrine disruptors and pharmaceuticals: implications for water sustain-ability//Water Science and Technology. 2010. Vol. 61, № 1. Р. 145-154
Strategic Survey of Therapeutic drugs in the rivers Po and Lambro in Northern Italy/D. Calamari //Environmental Science and Technology. 2003. Vol. 37. P. 1241-1248
Ternes T.A. Occurrence of drugs in German sewage treatment plants and rivers//Water Research. 1998. Vol. 32. P. 3245-3260
Toxic effects of the non-steroidal anti-inflammatory drug diclofenac. Part II: cytological effects in liver kidney, gills and intestine of rainbow trout (On-corhunchus mykiss)/R. Triebskom //Aquatic Toxicology. 2004. Vol. 68, № 2. P. 151156.
Toxicity assessment of papaverine hydrochloride and cultures of rat hepafocytes/J.C. Davila //In Vitro Cellular and Developmental Biology. 1990. Vol. 26. P. 515-524
Toxicological review of quinoline. In support of summary information of the integrated risk information system (IRIS)/J.J. Liccione //Environmental Protection Agency. 2001. URL: www.epa.gov/iris/toxreviews/1004tr.pdf (дата обращения: 10.09.2014)
Vahkova M. Biodegradability analysis of pharmaceuticals used in developing countries; screening with OxiTop ® -C 110: Final thesis/Magdalena Vafikova. Tampere, 2011. 73 рp
Wu S., Zhang L., Chen J. Paracetamol in the environment and its degradation by microorganisms//Applied Microbiology and Biotechnology. 2012. Vol. 96, № 4. P. 875-884
Zweiner C. Occurrence and analysis of pharmaceuticals and their transformation products in drinking water treatment//Analytical and Bioanalytical Chemistry. 2007. Vol. 387. P. 1159-1162

Еще

Статья научная