Recent venous thromboembolism pharmacoprophylaxis. Is laboratory control needed?

Individualization of antithrombotic drugs prescription in hospital conditions involves ensuring antithrombotic effect and at least nonincreasing of side effects and complications risk. It is impossible to achieve this without relying on laboratory tests. Blood coagulation tests (activated partial thromboplastin time, prothrombin time, determination of factor Ха activity, etc.) are performed on routine coagulometers (automatic and semi-automatic) that do not require any “special” equipment. At the same time becoming routine they reduce the cost of individual treatment and thereby reduce the overall costs of health care setting. Today decision choice of antithrombotic prophylaxis is based not only on clinical factors, but also on product properties, first of all on “value of one product unit”. But, perhaps, the most important for practical application of modern pharmacological and diagnostic tools is the postulate that «UNPROFITABLE PRODUCT (drug, test, organizational decision) DOESN’T BECOME MASS AND DOESN’T HOLD IN MARKET!».