The enzyme-inducing effect of the original anticonvulsant galodif is a modulating time factor, prospects for clinical use in the treatment of paroxysmal disorders
Автор: Shushpanova T.V., Novozheeva T.P., Vasilieva O.A., Udut V.V.
Журнал: Сибирский вестник психиатрии и наркологии @svpin
Рубрика: Психофармакотерапия
Статья в выпуске: 4 (121), 2023 года.
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Introduction. Improving pharmacotherapy is possible through the creation of new drugs and optimization of therapeutic monitoring. This approach can be implemented provided that the characteristics of the biotransformation of the drug by enzymes of the liver monooxygenase system (MOS), its pharmacokinetics and pharmacodynamics in the body are studied.
Anticonvulsant, galodif, paroxysm, liver, cytochrome p450, microsomal oxidation system, pharmacokinetic
Короткий адрес: https://sciup.org/142239824
IDR: 142239824 | DOI: 10.26617/1810-3111-2023-4(121)-61-69