Fish-method: technique of cytogenetic retrospective dose evaluation

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The purpose of this work was to submit the review of data of the scientific literature devoted to a FISH method as a way of cytogenetic retrospective dose evaluation. Problems of cytogenetic retrospective assessment of a dose in general; molecular and biological bases of a FISH-method; types of chromosome aberrations identified by means of a FISH-method; the principles of creation of dose curves for the FISH-registered chromosome translocations have been considered. The conclusion is drawn on need of attraction of three-color and multi-color variants of this technique to retrospective dose evaluation.

Fish-метод, fish-method, chromosome aberrations, peripheral blood lymphocyte culture, dose evaluation

Короткий адрес: https://sciup.org/14918385

IDR: 14918385

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