Complex treatment of tumors of the oral cavity using of photodynamic therapy

From 2003 to 2010 51 patients with tumors of oral cavity were treated. The location of the tumor, its size, prior treatment, and the patient's clinical status are the main indications for choosing the tactics of treatment. According to all above-mentioned all patients were divided into 4 clinical groups: only photodynamic therapy (PDT); surgery and photodynamic therapy; photodynamic therapy and gamma-ray therapy and/or simultaneous polychemotherapy; photodynamic therapy and interstitial neutron therapy by pin sources of californium-252. Complete response of tumor after PDT was independently of its localization and extent of spread in 41 patients (80.4 %), partial response - in 8 patients (15.7 %), stabilization - in 2 patients (3,9 %). Thus, overall result of treatment, i.e. the complete and partial response, amounted to 96.1 %. The 2-overall survival years rate was 71.7±7.8 %. PDT was developed as the new method of organ retaining treatment of therapy of oral cavity tumors in combination with the traditional methods of treatment. PDT can be effectively used for treatment of patients with primary, recurrent or residual tumors of oral cavity.