Hematological and biochemical parameters of rats under acute intoxication cyanopyrethroids

One of the most commonly used pyrethroids in agriculture is Fastac (а-cypermethrin) and Kinmiks (P-cypermethrin). Fastac is the most highly effective insecticide to kill insect pests on alfalfas, rapes, wheats, potatoes, sugar beets, grapes, peas, mustards and forest crops, vegetables and fruits. The insecticide is characterized by low doses of application. It has a complete destructive effect on problem and specific pests. It has repellent and antifidant properties. Kinmiks - fairly common insecticide contact-intestinal action against leaf-eating and sucking pests. It is characterized by a lightning destructive effect on these insects. Getting into the body, the insecticide causes paralysis of the nervous system of the insect and then his death. This insecticide is very effective against both adults and insect larvae. In the available literature data on the toxicity of kinmiks to warm-blooded animals do not exist. The authors carried out researches on the study of hematological and biochemical parameters of the blood of white rats at acute intoxication with cyanopyrethroids (а-cypermethrin and P-cypermethrin). The results of studies of hematological and biochemical parameters indicates that poisoning of white rats with cyanopirethroids in an absolutely lethal dose is accompanied by a significant increase in the blood of animals of count of leukocytes, glucose and MDA, as well as activities of ALT, AST and alkaline phosphatase.