Hemodynamic and clinical effectiveness of the bone marrow cell transplantation in treatment of critical ischemia of the lower extremities

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The goal is to study the hemodynamic and clinical effectiveness of bone marrow cell autotransplantation in critical limb ischemia in comparison with revascularizing osteotrepanation and lumbar sympathectomy. Material and methods. The analysis of a comprehensive examination and treatment of 99 patients with critical lower limb ischemia, divided into 3 statistically homogeneous groups, was carried out. In the first group, classical revascularizing osteotrepanation was performed, in the second - lumbar sympathectomy, and in the third - implantation of autologous bone marrow cells. Hemodynamic efficacy was evaluated by increasing rheovasographic, ankle-brachial and photoplethysmographic indices, painless walking distance, clinical - by improving the status of patients on the scale of Ruterford et al. Results. After 1 year, the volumetric blood flow in the ischemic limb after implantation of autologous bone marrow cells was 2.1 times higher than after revascularizing osteotrepanation and 2...

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Critical ischemia, lower limbs, lumbar sympathectomy, autologous bone marrow cell implantation, revascularizing osteotrepanation

Короткий адрес: https://sciup.org/140249358

IDR: 140249358   |   DOI: 10.25881/BPNMSC.2020.22.20.004

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