Hemopoetic action of kaliksarens

The effect of sulfonate calixarene on hematopoiesis of laboratory animals was studied. It was shown that with the introduction of the drug in rabbits in the experimental groups, an increase in the number of platelets by more than 2 times is observed. There is also a slight increase in the number of red blood cells and lymphocytes. The average leukocyte counts in the blood of rabbits of the experimental groups were within the physiological norm and were higher than the control by the end of the experiment from 0.8 to 1.8 thousand in 1 mm3. The average values of red blood cells and hemoglobin in the experimental groups were higher than the control by an average of 20 %. The greatest changes in the morphological composition of the blood of laboratory animals are observed with subcutaneous administration of the drug and with oral administration at a dose of 3 mg/kg. The stimulating effect of sulfonate calixarene on hematopoiesis processes has been proven.