Hepatoprotective effect of milk thistle oil

In the experiment, it was proved that the use of milk Thistle oil prevents the development of hepato-toxic action of carbon tetrachloride in dogs. The use of herbal drug prevents the activation of processes of lipid peroxidation, which was manifested by the decrease in the level of malondialdehyde in the serum of the animals treated with carbon tetrachlo-ride. In the group of animals treated with thistle oil on the background of administration of xenobiotic, on the 10-th day of the experiment, the MDA level in the blood serum was by 30.6 % lower than in the animals receiving only xenobiotic. Stabilizing effect of milk thistle oil revealed toxic hepatitis of dogs, which was manifested by normalization of the con-tent of aminotransferases in blood serum. ALT ac-tivity in animals, taking both herbal drug and model xenobiotic on the 10-th day of the experiment was by 28.9 % lower (P