Glucocorticoid-dependent regulation of free-radical oxidation in skates

Purpose. The search for metabolic markers of performance in skaters based on indicators of glucocorticoid-dependent indicators of free radical oxidation.Material and methods. The study was performed on 24 volunteer skaters in the autumn and winter periods of the training macrocycle. The athletes estimated the effectiveness of the competitive period in terms of the passage of distances of 500, 1000 and 1500 meters. The plasma levels of cortisol, the activity of prooxidant and antioxidant enzymes were determined. The intensity of lipid peroxidation was determined in erythrocytes. Results. Negative correlations between the time of passage of a distance, the content of cortisol and the activity of prooxidant and antioxidant enzymes were found. Athletes in the autumn competitive period, the content of cortisol was higher than in the autumn period. Accordingly, in the autumn period, the activity of platelet MAO-B and myeloperoxidase was higher. In contrast, the activity of antioxidant enzymes was lower. Conclusion. The presence of correlations between performance and glucocorticoid-dependent indicators of free radical oxidation during training periods opens up prospects for the establishment of new markers of the effectiveness of the training process. There is an opportunity for biochemical indicators of training cycles topredict sports results in competitions.