Population groups with high-risk of late radiation effects

Based on clinical and epidemiological analysis of the data obtained from long-term follow-up of the residents of the Techa riverside the study presents certain criteria, which can be used to identify high-risk groups (HRG) with respect to carcinogenic radiation effects. The factors of carcinogenic radiation risk have been determined on the basis of the analysis of radiation exposure markers (frequency of CD3-CD4+ lymphocytes, genomic translocations in peripheral blood lymphocytes) and biologic markers of susceptibility to cancers conditioned by the status of the highly radio-sensitive immunity system. Carcinogenic radiation risk factors can be taken into consideration along with other cancer risk factors in identifying HRGs among the population exposed to radiation.