Influence of night blood pressure on fetal, pregnancy and childbirth complications

Hypertensive disorders complicate approximately 5-7 % of pregnancies worldwide. Hypertension is one of the main causes of maternal and fetal morbidity and mortality, especially when high blood pressure leads to preeclampsia. The subtypes of arterial hypertension (AH) (elevated systolic blood pressure (SBP), elevated diastolic blood pressure (DBP), SBP and DBP simultaneously) were studied in the general population. However, little insight is available on the prognostic effects of different subtypes of isolated nocturnal hypertension during pregnancy. The objective of the trial is to evaluate the prognostic values of different subtypes of isolated nocturnal hypertension in fetal, pregnancy and childbirth complications. Moreover, the task is to compare the nocturnal AH and normal blood pressure influence.on complication development. Materials and Methods. The trial enrolled 174 pregnant women: 44 women with isolated nocturnal hypertension and 130 women without high blood pressure. All women underwent 24-hour blood pressure monitoring. Results. The authors revealed the link between isolated nocturnal hypertension and edema, proteinuria, threatened miscarriage, fetoplacental insufficiency, premature amniotic fluid leak, accelerated labor, premature birth, and intrauterine growth restriction. Conclusion. The knowledge on frequency of complications in pregnant women with isolated nocturnal hypertension in comparison with pregnant women without hypertension, as well as on the role of nocturnal AH subtypes will help physicians to carry out preventive and therapeutic measures and, thus, reduce the development of severe complications.