Pathomorphological changes in vital organs in pancreonecrosis

Objective. The aim of the paper is to study pathomorphological changes in vital organs in deceased patients, depending on the timeliness of medical care and the state of the pancreas, namely, aseptic (fat and hemorrhagic) and septic pancreatic necrosis. Materials and Methods. The authors studied pathomorphological changes in vital organs of 55 patients who died of pancreatic necrosis, who had/had not undergone inpatient treatment for it. Pathoanatomical studies were conducted in Ulyanovsk Regional Bureau of Forensic Medical Examinations (2010-2017). Results. Brain edema was noted only in patients with hemorrhagic pancreatic necrosis (7 cases). It proves that various forms of pancreatic necrosis have different destructive effects on the brain. The authors observed that this indicator was higher in the patients, who had not undergone any hospital treatment. This fact proves that the absence of intensive therapy contributes to the development of pancreatic necrosis. Conclusion...