Identification of human serum albumin alkylated adduct with mass-spectometry methods
Автор: Krasnov I.A., Podolskaya E.P., Goncharov N.V., Babakov V.N., Glashkina L.M., Ermolaeva E.E., Dubrovky Ya. A., Prokofeva D.S., Voitenko N.G., Smolihina T.I., Polyakov N.B., Radilov A.S., Krasnov N.V.
Журнал: Научное приборостроение @nauchnoe-priborostroenie
Рубрика: Масс-спектрометрия для биотехнологии. Интерпретация данных, методология, применение
Статья в выпуске: 4 т.18, 2008 года.
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A protein fraction of human blood serum exposed in vitro to sulfur mustard (bis-2-chloroethylsulfide, HD) has been studied using MALDI-TOF and ESI-TOF methods, and a number of HD-modified albumin peptides have been identified. A tryptic peptide with molecular mass of 2536.19 Da has been identified by MALDI-TOF and MALDI-TOF-TOF methods. In addition 3 modified chymotryptic peptides with molecular masses 838.37 Da, 1200.53 Da, 2378.13 Da were found with ESI-TOF method.
Короткий адрес: https://sciup.org/14264572
IDR: 14264572
