In-silico docking studies of calendoflavobioside of Calendula officinalis Linn. against matrix metalloproteinase 8 and 12 on wound healing

Bioactive compounds are a rich source of preventive substances for many diseases. In the present study was attempt to evaluate the in silico docking studies of calendoflavobioside of Calendula officinalis Linn. on wound healing. The compound calendoflavobioside were screened for the wound healing biomarker matrix metallo proteinases 8 and 12 by molecular docking. The result of the study indicates that calendoflavobioside has good affinity with MMP 8(-3.00kcal/mol) and MMP 12(-3.08kcal/mol).