Surgical site infections after lung resection

Introduction. To identify prognostic indicators associated with the development of surgical site infections (SSIs) following elective thoracotomy. Materials and methods. The study was conducted at the Thoracic Oncology Surgery Department of the State Healthcare Institution of Ulyanovsk Regional Cancer Center. The analysis included patients who underwent lobectomy or atypical resection between January 1, 2021, and December 31, 2023 (Database RU 2024622259 dated May 24, 2024). A total of 468 patients were included, of whom 32 (6,8 %) developed SSIs. Results. The incidence of SSIs was 32/468 (6,8 %). Univariate analysis revealed statistically significant predictors of SSI development: age (p = 0,022), presence of diabetes mellitus (p < 0,001) and obesity (p = 0,043), the extent of surgical intervention (p = 0.003) and its duration (p < 0.001), the stage of COPD (p = 0,043), intraoperative blood loss (p < 0.001), and postoperative air leakage (p < 0,001). Multivariate analysis identified statistically significant indicators: the presence of diabetes mellitus (OR 7,286; 95 % CI 3,083–17,219; p < 0,001), surgery duration (OR 1.013; 95 % CI 1.004–1.023; p = 0.007), volume of blood loss (OR 1,004; 95 % CI 1,001–1,007; p = 0,007), and prolonged air leakage (OR 4,444; 95 % CI 1,677–11,775; p = 0,003). Conclusion. The incidence of SSIs following surgical treatment for lung diseases was 32 cases (6,8 %), of which 59,4 % corresponded to grade 2 on the Southampton scale.