The outcomes of pregnancy and childbirth in Rh-conflict pregnancy

In order to study the characteristics of pregnancy and childbirth, as well as perinatal outcomes in patients with abrupt and conflict pregnancy, a retrospective analysis was conducted of 42 relatives of patients with Rh sensitization, born in the period 2018-2019, as well as 10 hospital inpatients of newborns with HDN. It was revealed that the most important risk factor for development is the lack of timely specific prophylaxis with anti-Rh immunoglobulin. Prognostically unfavorable in relation to the development of forms of HDN is early (up to 20 weeks) detection of high antibody titers (1:16 and more) and its increase during pregnancy, as well as the growing and ‘jumping’ character of the dynamics of the Rh antibody titer. The most informative method for diagnosing the severity of hypertension is the dopplerometry of the blood flow in the fetal AGR, allowing resolving the issue of timely MIC to the fetus. 10 newborns (32%) were diagnosed with HDN of varying severity.